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Transcriptional memory of gene expression enables adaptation to repeated stimuli across many organisms. However, the regulation and heritability of transcriptional memory in single cells and through divisions remains poorly understood. Here, we combined mi ...

Introduction: Personally meaningful past episodes, defined as episodic memories (EM), are subjectively re-experienced from the natural perspective and location of one's own body, as described by bodily self-consciousness (BSC). Neurobiological mechanisms o ...

The stress response facilitates survival through adaptation and is intimately related to cognitive processes. The Morris water maze task probes spatial learning and memory in rodents and glucocorticoids (i.e. corticosterone (CORT) in rats) have been sugges ...

Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a genetic disease associated with an increased risk for schizophrenia and a specific cognitive profile. In this paper, we challenge the current view of spared verbal memory in 22q11.2DS by investigating v ...

Continuous attractor models of working-memory store continuous-valued information in continuous state-spaces, but are sensitive to noise processes that degrade memory retention. Short-term synaptic plasticity of recurrent synapses has previously been shown ...

When moving, the spatiotemporal unfolding of events is bound to our physical trajectory, and time and space become entangled in episodic memory. When imagining past or future events, or being in different geographical locations, the temporal and spatial di ...

Synaptic changes induced by neural activity need to be consolidated to maintain memory over a timescale of hours. In experiments, synaptic consolidation can be induced by repeating a stimulation protocol several times and the effectiveness of consolidation ...

Long-lasting memories form the basis of our identity as individuals and lie central in shaping future behaviours that guide survival. Surprisingly, however, our current knowledge of how such memories are stored in the brain and retrieved, as well as the dy ...

Fear and other anxiety disorders are extraordinarily robust and difficult to treat. Among the most effective treatments for anxiety disorders are exposure-based therapies, during which a patient is repeatedly confronted with the originally fear-eliciting s ...

SRC - Gestion

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Single-Cell Tracing Dissects Regulation of Maintenance and Inheritance of Transcriptional Reinduction Memory

Subjective feeling of re‐experiencing past events using immersive virtual reality prevents a loss of episodic memory

Constitutive differences in glucocorticoid responsiveness are related to divergent spatial information processing abilities

Long-term verbal memory deficit and associated hippocampal alterations in 22q11.2 deletion syndrome

Stability of working memory in continuous attractor networks under the control of short-term plasticity

Building the Arrow of Time ... Over Time: A Sequence of Brain Activity Mapping Imagined Events in Time and Space

Optimal Stimulation Protocol in a Bistable Synaptic Consolidation Model

The mysteries of remote memory

In the pursuit of the fear engram: identification of neuronal circuits underlying the treatment of anxiety disorder