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Publications associées (29)

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Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis

Nicola Harris, Lalit Kumar Dubey

Lymphatic growth (lymphangiogenesis) within lymph nodes functions to promote dendritic cell entry and effector lymphocyte egress in response to infection or inflammation. Here we demonstrate a crucial role for lymphotoxin-beta receptor (LT beta R) signalin ...

Springer Nature2017

Fixed and mobile-bearing total ankle prostheses: Effect on tibial bone strain

Alexandre Terrier, Xavier Crevoisier, Maïka Réane Guillemin, Caroline Sieger Fernandes

Background Total ankle replacement is associated to a high revision rate. To improve implant survival, the potential advantage of prostheses with fixed bearing compared to mobile bearing is unclear. The objective of this study was to test the hypothesis th ...

Elsevier2017

Elucidating the role of lymphatic vessels within the tumor microenvironment of breast cancer

Ingrid Maria van Mier

Breast cancer is the most common cancer in women worldwide, with an estimated 1.7 million newly diagnosed cases in 2012. Despite the many clinical manifestations, metastatic disease is the main cause of death, and is responsible for 90% of all breast cance ...

EPFL2017

Iron oxide nanoparticles for diagnosis and therapy of lymph node metastases

Débora Bonvin

This thesis presents the synthesis, coating and characterization of iron oxide nanoparticles (IONPs) with properties especially designed for the ultimate simultaneous MRI detection and hyperthermia treatment of lymph node metastases, a combination called t ...

EPFL2017

Full-field measurement of micromotion around a cementless femoral stem using micro-CT imaging and radiopaque markers

Dominique Pioletti, Alexandre Terrier, Valérie Hélène Emilie Malfroy Camine

A good primary stability of cementless femoral stems is essential for the long-term success of total hip arthroplasty. Experimental measurement of implant micromotion with linear variable differential transformers is commonly used to assess implant primary ...

Elsevier2016

Micromotion and fluid flow around cementless femoral components in total hip arthroplasty

Valérie Hélène Emilie Malfroy Camine

Cementless total hip arthroplasty is a highly successful and reliable procedure to restore joint function and reduce pain in patients with severe osteoarthritis. Nevertheless, despite the technical advances over the last decades in the development of cemen ...

EPFL2016

In-situ photopolymerized and monitored implants: successful application to an intervertebral disc replacement

Dominique Pioletti, Christophe Moser, Andreas Schmocker, Azadeh Khoushabi

Photopolymerization is a common method to harden materials initially in a liquid state. A surgeon can directly trigger the solidification of a dental implant or a bone or tissue filler by using ultra-violet light. Traditionally, photopolymerization has bee ...

Spie-Int Soc Optical Engineering2016

Lymphatic vessels regulate immune microenvironments in human and murine melanoma

Melody Swartz, Manuel Andreas Fankhauser

Lymphatic remodeling in tumor microenvironments correlates with progression and metastasis, and local lymphatic vessels play complex and poorly understood roles in tumor immunity. Tumor lymphangiogenesis is associated with increased immune suppression, yet ...

Amer Soc Clinical Investigation Inc2016

Collecting Lymphatic Vessel Permeability Facilitates Adipose Tissue Inflammation and Distribution of Antigen to Lymph Node-Homing Adipose Tissue Dendritic Cells

Melody Swartz, Wei Wang

Collecting lymphatic vessels (CLVs), surrounded by fat and endowed with contractile muscle and valves, transport lymph from tissues after it is absorbed into lymphatic capillaries. CLVs are not known to participate in immune responses. In this study, we ob ...

American Association of Immunologists ; Oxford University Press2015