Publication

The Nano-Scale Mechanical Properties of the Extracellular Matrix Regulate Dermal Fibroblast Function

Publications associées (28)

Immunosuppressive roles of Activin-A in melanoma and characterization of its precursor cleavage

Activin-A, a transforming growth factor ê µ family member, is a pleiotropic cytokine with diverse functions in development, fertility, adult tissue homeostasis, and aging. Accordingly, deregulation of Activin-A signaling has been associated with many patho ...

EPFL2022

Wireless soft microscale actuators and robotic devices to study mechanobiology

Raquel Filipa Penacho Parreira

Tissues morphogenesis and homeostasis involve the spatiotemporal regulation of mechanics at multiple scales. Characterization of mechanical properties of biological systems as well as investigating the effects of mechanical forces on biological function ar ...

EPFL2021

Laser-induced liquid micro-jets for drug delivery

Jan Krizek

Jet injection devices have been studied and developed for transdermal drug delivery to avoid the use of needles. Such contact-less devices provide several advantages such as better dose control, lateral and depth localisation, lower collateral damage than ...

EPFL2021

A new paradigm for leprosy diagnosis based on host gene expression

Stewart Cole, Philippe Busso, Andrej Benjak, Charlotte Avanzi, Thyago Leal Calvo

Author summary ...

PUBLIC LIBRARY SCIENCE2021

Rapid Noninvasive Skin Monitoring by Surface Mass Recording and Data Learning

Hubert Girault, Horst Pick, Natalia Gasilova, Andreas Stephan Lesch, Tzu-En Lin, Yingdi Zhu, Milica Jovic

Skin problems are often overlooked due to a lack of robust and patient-friendly monitoring tools. Herein, we report a rapid, noninvasive, and high-throughput analytical chemical methodology, aiming at real-time monitoring of skin conditions and early detec ...

2021

Single-cell lipidomics reveals a role for cell-to-cell sphingolipid heterogeneity in fibroblast activation

Laura Capolupo

Cell-to-cell variability plays a key role in tissue patterning by setting initial asymmetry that primes cell fate decisions. Fluctuations in the activity of regulatory molecules can commit individual cells to divergent differentiation pathways, and cell-to ...

EPFL2021

Electronic Skins for Healthcare Monitoring and Smart Prostheses

Laurent Mirko Dejace, Stéphanie Lacour, Haotian Chen

The human skin is a unique organ that embeds multiple functions that no artificial systems can currently replicate. Advances in materials science and engineering are driving the design of electronic skins-large-area sensor arrays that mimic some sensory mo ...

ANNUAL REVIEWS2021

Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced by High-Fat Diet in an MMP-Dependent Mechanism

Nikolaos Stergiopoulos, Rafaela Fernandes Da Silva, Mikaël Nils Sturny, Fabiana Pereira Da Costa Fraga, Léa Liliane Colette Anguenot, Maiia Bragina, Augusto Martins Lima

Background: An increased fibrosis of the corpora cavernosa is a prevalent process that underlies most cases of erectile dysfunction. Apelin, an endogenous circulating peptide, has been documented as an important effector on cardiovascular homeostasis, cont ...

ELSEVIER SCI LTD2021