Publications associées à Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV

Publications associées (13)

A dual-color PAX7 and MYF5 in vivo reporter to investigate muscle stem cell heterogeneity in regeneration and aging

Increasing evidence suggests that the muscle stem cell (MuSC) pool is heterogeneous. In particular, a rare subset of PAX7-positive MuSCs that has never expressed the myogenic regulatory factor MYF5 displays unique self-renewal and engraftment characteristi ...

2024

Head-to-Head Comparison of Learning Curves Between QFR and FFRangio Software Users

Mehdi Ali Gadiri

Background: Quantitative flow ratio (QFR) and FFRangio are angiography-based technologies used to perform functional assessment of coronary lesions from angiographic images, validated across multiple clinical studies. There is limited information on the le ...

2024

Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems

Johan Auwerx, Olaia Maria Naveiras Torres-Quiroga, Frédérica Schyrr, Charles Christopher Bataclan

Aging compromises hematopoietic and immune system functions, making older adults especially susceptible to hematopoietic failure, infections and tumor development, and thus representing an important medical target for a broad range of diseases. During agin ...

SPRINGERNATURE2023

c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs

Matthias Lütolf, Jakob Josef Langer

c-MAF, highly expressed in villus small intestinal enterocytes, coordinates transcriptional programs for nutrient absorption. Enterocyte-specific c-MAF inactivation impairs dietary lipid handling but also leads to tuft cell expansion and adaptive gut lengt ...

ROCKEFELLER UNIV PRESS2022

Autoantibodies against type I IFNs in patients with Ph-negative myeloproliferative neoplasms

Alessandro Borghesi

AMER SOC HEMATOLOGY2022

Deep Neural Network to Accurately Predict Left Ventricular Systolic Function Under Mechanical Assistance

Simone Deparis, Luca Pegolotti

Characterizing left ventricle (LV) systolic function in the presence of an LV assist device (LVAD) is extremely challenging. We developed a framework comprising a deep neural network (DNN) and a 0D model of the cardiovascular system to predict parameters o ...

FRONTIERS MEDIA SA2021

Hypoxic Incubation Conditions for Optimized Manufacture of Tenocyte-Based Active Pharmaceutical Ingredients of Homologous Standardized Transplant Products in Tendon Regenerative Medicine

Romain Hamelin, Florence Armand, Diego Chiappe

Human fetal progenitor tenocytes (hFPT) produced in defined cell bank systems have recently been characterized and qualified as potential therapeutic cell sources in tendon regenerative medicine. In view of further developing the manufacture processes of s ...

MDPI2021

Mechanical Immunoengineering of T-cells for Therapeutic Applications

Li Tang, Armand Kurum, Kewen Lei

T cells, a key component in adaptive immunity, are central to many immunotherapeutic modalities aimed at treating various diseases including cancer, infectious diseases, and autoimmune disorders. The past decade has witnessed tremendous progress in immunot ...

American Chemical Society2020

Longitudinal expression changes are weak correlates of disease progression in Huntington's disease

Irina Krier

Huntington's disease is a severe but slowly progressive hereditary illness for which only symptomatic treatments are presently available. Clinical measures of disease progression are somewhat subjective and may require years to detect significant change. T ...

OXFORD UNIV PRESS2020

Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice

Elena Goun, Pavlo Khodakivskyi

The kidney's inherent complexity has made identifying cell-specific pathways challenging, particularly when temporally associating them with the dynamic pathophysiology of acute kidney injury (AKI). Here, we combine renal cell-specific luciferase reporter ...

Springer2019

Neurochemical profile differentiation of glioma induced by cancer stem cells expressing WIF1: a 1H-MRS longitudinal study at 14.1T

Rolf Gruetter, Cristina Ramona Cudalbu Moldovan, Bernard Lanz, Marta Lai

2014

Dielectric spectroscopy in a microfabricated flow cytometer

Shady Didier Gawad

In this thesis, a new microfabricated flow cytometer for single cell discrimination based on dielectric spectroscopy is presented. Integrated tools for rapid in-flow cell handling are also demonstrated. Signal amplification and analysis as well as the chip ...

EPFL2004

Treatment of diseases of the central nervous system using encapsulated cells

Patrick Aebischer

1999