Publication

The N-terminal Ac-EEED sequence plays a role in alpha-smooth-muscle actin incorporation into stress fibers

Publications associées (32)

Functional and structural characterization of Serratia marcescens ExbB: determinants of the interaction with HasB/TonB

ExbBD is part of a cytoplasmic membrane molecular motor driven by the proton-motive force. It belongs to the larger family of motors involved in nutriment import across the outer membrane of Gram-negative bacteria (ExbBD), flagellar rotation (MotAB) or lat ...

2021

Engineered Extracellular Matrices with Integrated Wireless Microactuators to Study Mechanobiology

Mahmut Selman Sakar, Erik Mailand, Nikolaos Bouklas, Fazil Emre Uslu

Mechanobiology explores how forces regulate cell behaviors and what molecular machinery are responsible for the sensing, transduction, and modulation of mechanical cues. To this end, probing of cells cultured on planar substrates has served as a primary ex ...

Wiley2021

Soft functional fibers for mechanical sensing and actuation

Andreas Leber

The measurement and generation of mechanical deformations is a key functionality in health monitoring, human-machine interaction, and soft robotics. However, current methods typically rely on small and hard transducers, which result in poor performance, cu ...

EPFL2021

The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid-liquid phase separation

Helen Lindsay

Liquid-liquid phase separation (LLPS) of proteins and RNAs has emerged as the driving force underlying the formation of membrane-less organelles. Such biomolecular condensates have various biological functions and have been linked to disease. The protein F ...

2021

In Vitro-Evolved Peptides Bind Monomeric Actin and Mimic Actin-Binding Protein Thymosin-β4

Christian Heinis, Davide Bertoldo, Raphael Johannes Gübeli, Jonas Alfred Karl Wilbs, Ganesh Kumar Mothukuri

Actin is the most abundant protein in eukaryotic cells and is key to many cellular functions. The filamentous form of actin (F-actin) can be studied with help of natural products that specifically recognize it, as for example fluorophore-labeled probes of ...

2021

Exploring optically active defects in wide-bandgap materials using fluorescence microscopy

Evgenii Glushkov

Defects in solid-state systems can be both detrimental, deteriorating the quality of materials, or desired, thanks to the novel functionality they bring. Optically active point defects, producing fluorescent light, are a great example of the latter. Natura ...

EPFL2021

Distributed Temperature Sensing Based on φ-OTDR Using Back-reflection-enhanced Fiber

Luc Thévenaz, Li Zhang, Malak Mohamed Hossameldeen Omar Mohamed Galal, Suneetha Sebastian

Distributed temperature sensing with 10 dB back-reflection-enhanced fiber is performed based on φ-OTDR. While the temperature sensitivity of such fibers is similar to that of standard single-mode fibers, a 3-times higher temperature resolution is observed. ...

Optical Society of America2021

Single-cell lipidomics reveals a role for cell-to-cell sphingolipid heterogeneity in fibroblast activation

Laura Capolupo

Cell-to-cell variability plays a key role in tissue patterning by setting initial asymmetry that primes cell fate decisions. Fluctuations in the activity of regulatory molecules can commit individual cells to divergent differentiation pathways, and cell-to ...

EPFL2021

Cell penetration efficiency analysis of different atomic force microscopy nanoneedles into living cells

Marcos Penedo Garcia

Over the last decade, nanoneedle-based systems have demonstrated to be extremely useful in cell biology. They can be used as nanotools for drug delivery, biosensing or biomolecular recognition inside cells; or they can be employed to select and sort in par ...

Nature Research2021

Ultimate Feature Sizes in Thermally Drawn Fibers: from Fundamental Analysis to Novel Functional Fibers

Inès Richard

The fiber thermal drawing process has emerged as a simple and scalable technique for the fabrication of multifunctional and flexible electronics. The integration of materials with various physical and functional properties in well-defined architectures ope ...

EPFL2021

Fiber-Shaped Electronic Devices

Mohammad Khaja Nazeeruddin

Textile electronics embedded in clothing represent an exciting new frontier for modern healthcare and communication systems. Fundamental to the development of these textile electronics is the development of the fibers forming the cloths into electronic dev ...

WILEY-V C H VERLAG GMBH2021

Seeing and Touching the Mycomembrane at the Nanoscale

John McKinney, Georg Fantner

Mycobacteria have unique cell envelopes, surface properties and growth dynamics, which all play a part in the ability of these important pathogens to infect, evade host immunity, disseminate and to resist antibiotic challenges. Recent atomic force microsco ...

American Society for Microbiology2021