Astrocytic beta(2)-adrenergic receptors mediate hippocampal long-term memory consolidation

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Synaptic plasticity underlies the brain’s ability to learn and adapt. While experiments in brain slices have revealed mechanisms and protocols for the induction of plasticity between pairs of neurons, how these synaptic changes are coordinated in biologica ...

Machine learning and data processing algorithms have been thriving in finding ways of processing and classifying information by exploiting the hidden trends of large datasets. Although these emerging computational methods have become successful in today's ...

By supporting the access of multiple memory words at the same time, Bit-line Computing (BC) architectures allow the parallel execution of bit-wise operations in-memory. At the array periphery, arithmetic operations are then derived with little additional o ...

We are constantly bombarded by sensory information and constantly making decisions on how to act. In order to optimally adapt behavior, we must judge which sequences of sensory inputs and actions lead to successful outcomes in specific circumstances. Neuro ...

This paper explores a novel application of textual semantic similarity to user-preference representation for rating prediction. The approach represents a user's preferences as a graph of textual snippets from review text, where the edges are defined by sem ...

Memory devices have returned to the spotlight due to increasing interest in using in-memory computing architectures to make data-driven algorithms more energy-efficient. One of the main advantages of this architecture is the efficient performance of vector ...

During fear learning, defensive behaviors like freezing need to be finely balanced in the presence or absence of threat-predicting cues (conditioned stimulus, CS). Nevertheless, the circuits underlying such balancing are largely unknown. Here, we investiga ...

Background: Understanding why only a subset of trauma-exposed individuals develop posttraumatic stress disorder is critical for advancing clinical strategies. A few behavioral (deficits in fear extinction) and biological (blunted glucocorticoid levels, sma ...

The CA1 region of the hippocampus is one of the most studied regions of the rodent brain, thought to play an important role in cognitive functions such as memory and spatial navigation. Despite a wealth of experimental data on its structure and function, i ...

Long-term memory formation relies on synaptic plasticity, neuronal activity-dependent gene transcription, and epigenetic modifications. Multiple studies have shown that HDAC inhibitor (HDACi) treatments can enhance individual aspects of these processes and ...

Astrocytic beta(2)-adrenergic receptors mediate hippocampal long-term memory consolidation

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Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

2D Nanosystems: Applications of 2D Semiconductors for In-Memory Computing

Bit-Line Computing for CNN Accelerators Co-Design in Edge AI Inference

Striatal Dopamine Signals and Reward Learning

KNNs of Semantic Encodings for Rating Prediction

How to Achieve Large-Area Ultra-Fast Operation of MoS 2 Monolayer Flash Memories?

A striatal circuit balances learned fear in the presence and absence of sensory cues

Blunted Glucocorticoid Responsiveness to Stress Causes Behavioral and Biological Alterations That Lead to Posttraumatic Stress Disorder Vulnerability

Community-based reconstruction and simulation of a full-scale model of region CA1 of rat hippocampus

The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning