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Spillway blockage caused by large wood in reservoirs

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MDPI2023

A single-cell-based characterization of mammalian adipose stem and progenitor cell heterogeneity and function

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White adipose tissue (WAT) is a cellularly heterogeneous endocrine organ that not only serves as a reservoir for storing and releasing energy but also actively participates in metabolic homeostasis. Given the current rise in obesity and its associated como ...

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Statistical learning quantifies transposable element-mediated cis-regulation

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Self-renewal and differentiation of stem and progenitor cells are tightly regulated to ensure tissue homeostasis. This regulation is enabled both remotely by systemic circulating cues, such as cytokines and hormones, and locally by various niche-confined f ...

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The Metaverse as a Virtual Model of Platform Urbanism: Its Converging AIoT, XReality, Neurotech, and Nanobiotech and Their Applications, Challenges, and Risks

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With their exponentially rising computational power, digital platforms are heralding a new era of hybrid intelligence. There has recently been much enthusiasm and hype that the Metaverse has the potential to unlock hybrid intelligence. This is premised on ...

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X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main trigger of XCI, is controlled in the mouse by an interplay of lncRNA genes (LRGs), some of which evolved concom ...

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Playing Brains: The Ethical Challenges Posed by Silicon Sentience and Hybrid Intelligence in DishBrain

The convergence of human and artificial intelligence is currently receiving considerable scholarly attention. Much debate about the resulting Hybrid Minds focuses on the integration of artificial intelligence into the human brain through intelligent brain- ...

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Hydromorphological assessment of sediment augmentation measures in gravel-bed rivers

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In the riverine environment, the riverscape, sediment and flow regime are essential drivers for natural habitat dynamics. Today, most water courses in Europe are regulated, and their natural dynamics are impaired. Flood releases coupled with the artificial ...

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Bioengineering human mini-intestines with in vivo-like complexity and function

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Biological research heavily relies on the use of animal models, which has made it difficult to answer specific questions about human biology and disease. However, with the advent of human organoids - miniature versions of tissues generated in 3D human stem ...

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Sperm-contributed centrioles segregate stochastically into blastomeres of 4-cell stage Caenorhabditis elegans embryos

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Whereas both sperm and egg contribute nuclear genetic material to the zygote in metazoan organisms, the inheritance of other cellular constituents is unequal between the 2 gametes. Thus, 2 copies of the centriole are contributed solely by the sperm to the ...

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The Bioaccumulation of Ionizable Organic Compounds in Fish Cell Lines

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Bioaccumulation is defined as the enrichment of a compound in an organism relative to the surrounding water or its food, and is an important endpoint in chemical risk assessment. Under laboratory conditions, bioaccumulation is measured as bioconcentration ...

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Short-term dynamics of drainage density based on a combination of channel flow state surveys and water level measurements

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Headwater streams often experience intermittent flow. Consequently, the flowing drainage network expands and contracts and the flowing drainage density (DD) varies over time. Monitoring the DD dynamics is essential to understand the processes controlling i ...

Wiley2023