The Biological Substrate of the Motoric Cognitive Risk Syndrome: A Pilot Study Using Amyloid-/Tau-PET and MR Imaging

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The thalamus is a collection of gray matter nuclei that play a crucial role in sensorimotor processing and modulation of cortical activity. Characterizing thalamic nuclei non-invasively with structural MRI is particularly relevant for patient populations w ...

Reconstitution of TDP-43 filaments that exhibit sequence and morphological features similar to those found in the brain helps to uncover a new mechanism for the formation and propagation of pathology in amyotrophic lateral sclerosis and other neurodegenera ...

TAR DNA-binding protein with 43 kD (TDP-43) is a partially disordered protein that misfolds and accumulates in the brains of patients affected by several neurodegenerative diseases. TDP-43 oligomers have been reported to form due to aberrant misfolding or ...

Purpose: Delineation of subtle lesions in magnetic resonance imaging (MRI)-negative patients is of great importance in preoperative epilepsy evaluation. The aim of our study was to explore the diagnostic value of the novel fluid and white matter suppressio ...

In spite of extensive work, inconsistent findings and lack of specificity in most neuroimaging techniques used to examine age- and gender-related patterns in brain tissue microstructure indicate the need for additional research. Here, we performed the larg ...

Perfusion CT is widely used in acute ischemic stroke to determine eligibility for acute treatment, by defining an ischemic core and penumbra. In this work, we propose a novel way of building on prior information for the automatic prediction and segmentatio ...

Efficient medical care fundamentally relies on the ability to provide a timely and accurate diagnosis. Thanks to advances in biomedical research, specific molecules called diagnostic molecular biomarkers have been discovered in the human body that help ind ...

Brain stroke is an age-related illness which has become a major issue in our ageing societies. Early diagnosis and treatment are of high importance for the full recovery of the patient, as reminded in Anglo-Saxon countries by the abbreviation FAST (Face, A ...

The present study evaluated the potential of using the phase of T-2* weighted MR images to characterize myelination during brain development and pathology in rodents at 9.4 T. Phase contrast correlated with myelin content assessed by histology and suggests ...

The process of protein aggregation, due to an incorrect protein folding, has very important implications in medicine. An increasing number of pathologies, including Alzheimer's and Parkinson's diseases, are associated unambiguously with the formation of la ...

The Biological Substrate of the Motoric Cognitive Risk Syndrome: A Pilot Study Using Amyloid-/Tau-PET and MR Imaging

Chattez avec Graph Search

Advancing Thalamic Nuclei Segmentation: The Impact of Compressed Sensing on MRI Processing

Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage

Recombinant Full-Length TDP-43 Oligomers Retain Their Ability to Bind RNAs, Are Not Toxic, and Do Not Seed TDP-43 Aggregation in Vitro

Fluid and White Matter Suppression Imaging and Voxel-Based Morphometric Analysis in Conventional Magnetic Resonance Imaging-Negative Epilepsy

Age- and gender-related differences in brain tissue microstructure revealed by multi-component T2 relaxometry

Bayesian Skip Net: Building on Prior Information for the Prediction and Segmentation of Stroke Lesions

A Comparison of Acoustic and Linguistics Methodologies for Alzheimer's Dementia Recognition

Quantitative susceptibility mapping classifies white matter lesions with different myelin and axonal content and quantifies diffuse pathology in MS

Nanoparticle-enhanced Imaging Based Plasmonic Biosensor

Sleep Spindles In Late Chronotypes

Corrigendum: A Cell Atlas for the Mouse Brain

Microwave Imaging of Brain Stroke : Contributions to Modeling and Inverse Problem Resolution

In vivo assessment of myelination by phase imaging at high magnetic field

Bloch Surface Wave Biosensing : Study of Optical Elements for the Early Detection of Protein Aggregation