Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria

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Influenza is an infectious respiratory illness caused by influenza viruses. Every year, it causes up to one billion cases of disease worldwide. Despite its high disease burden, the transmission pathway of influenza remains subject to debate. There is incre ...

The elderly population is highly susceptible to developing respiratory diseases, including tuberculosis, a devastating disease caused by the airborne pathogen Mycobacterium tuberculosis ( M.tb ) that kills one person every 18 seconds. Once M.tb reaches the ...

The World Health Organization highlights the urgent need to address the global threat posed by antibiotic-resistant bacteria. Efficient and rapid detection of bacterial response to antibiotics and their virulence state is crucial for the effective treatmen ...

Before the COVID-19 pandemic, viruses were not a major priority for the scientific community. Today, many events have changed the world and the importance of studying viruses, vaccines, and antiviral drugs is fully appreciated. The development of effective ...

Cells have evolved endocytic pathways to internalize different molecules, to regulate intra-cellular communication and their interaction with external environment. Pathogens have co-evolved with cells to exploit these processes for infections. In particula ...

Microorganisms, encompassing both uni- and multicellular entities, exhibit remarkable diversity as omnipresent life forms in nature. They play a pivotal role by supplying essential components for sustaining biological processes across diverse ecosystems, i ...

Bacteria are ubiquitous single cellular organisms. Compared to eukaryotic cells, bacteria have two unique characteristics: the membrane-less nucleoid and the cell wall built of peptidoglycan (PG). In most bacteria, a single circular chromosome is compacted ...

Ribosomes translate the genetic code into proteins. Recent technical advances have facilitated in situ structural analyses of ribosome functional states inside eukaryotic cells and the minimal bacterium Mycoplasma. However, such analyses of Gram-negative b ...

We study the bactericidal efficacy of surface dielectric barrier discharge low-temperature plasma treatments, powered by nanosecond high voltage pulses. We achieve similar to 4-log reduction in Escherichia coli population, after 10 min treatments, at a dis ...

Viral metagenomics is a useful tool for detecting multiple human viruses in urban sewage. However, more refined protocols are required for its effective use in disease surveillance. In this study, we investigated the performance of three different preampli ...

Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to the respective human host population has been invoked in this context. We aim ...

This work is driven by the effort towards increased environmental sustainability and aims to develop a new food packaging material based on renewable materials, and more specifically cellulose as the most abundant biomass resource on Earth. Focus was on mi ...

The present study aimed to fill the knowledge gap between the implications of intracellular and extracellular antibiotic resistance mechanisms may inflict on the inactivation pathways of the photo-Fenton process under mild conditions. It was thus designed ...

The synthesis of complex sugars is a key aspect of microbial biology. Cyclic beta-1,2-glucan (C beta G) is a circular polysaccharide critical for host interactions of many bacteria, including major pathogens of humans (Brucella) and plants (Agrobacterium). ...

This study explores the differences in performance and results by various versions of the ISORROPIA thermodynamic module implemented within the ECHAM/MESSy Atmospheric Chemistry (EMAC) model. Three different versions of the module were used, ISORROPIA II v ...

Mycobacterium Tuberculosis is a highly effective pathogen infecting nearly a third of the world's population. An M. tuberculosis infection starts when droplets containing bacteria enter an individual's lungs. The first host cells to contact the bacteria ar ...

Research on chipless and passive architectures for environmental sensing is generating high interest because they do not require any semiconductor components or batteries to operate, thus resulting in an eco-friendlier footprint. This study demonstrates a ...

Sometimes treatment effects are absent in a subgroup of the population. For example, penicillin has no effect on severe symptoms in individuals infected by resistant Staphylococcus aureus, and codeine has no effect on pain in individuals with certain polym ...

A major component of human skin oil is squalene, a highly unsaturated hydrocarbon that protects the skin from atmospheric oxidants. Skin oil, and thus squalene, is continuously replenished on the skin surface. Squalene is also quickly consumed through reac ...

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria

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Inactivation of influenza A virus in expiratory droplets and aerosol particles and the associated physicochemical drivers

Human alveolar lining fl uid from the elderly promotes Mycobacterium tuberculosis intracellular growth and translocation into the cytosol of alveolar epithelial cells

Machine learning method for the classification of the state of living organisms' oscillations

Peptide-based virucidal drugs

S-acylation and lipid exchange at the ER-Golgi membrane contact sites regulate pathogen entry in human cells

Microfluidic systems for infectious disease diagnostics

Resolving bacterial cell biology: from replisome dynamics to cell wall synthesis

Bactericidal effect of tetracycline in E. coli strain ED1a may be associated with ribosome dysfunction

In-Situ FTIR and Laser Induced Fluorescence RONS Characterization of Atmospheric Pressure Nanosecond-Pulsed Surface DBD Plasma for Indirect Treatments of E. Coli

Comparison of Three Viral Nucleic Acid Preamplification Pipelines for Sewage Viral Metagenomics

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania

Multilayer diffusion-barrier composites based on microfibrillated cellulose from wood, bacterial and algae sources

Homogeneous vs. heterogeneous photo-Fenton elimination of antibiotic-resistant bacteria bearing intracellular or extracellular resistance: Do resistance mechanisms interfere with disinfection pathways?

Structure-function analysis of the cyclic β-1,2-glucan synthase from Agrobacterium tumefaciens

Implementation of the ISORROPIA-lite aerosol thermodynamics model into the EMAC chemistry climate model (based on MESSy v2.55): implications for aerosol composition and acidity

Single-cell analysis of the interactions between Mycobacterium tuberculosis and macrophages

Degradable and Printed Microstrip Line for Chipless Temperature and Humidity Sensing

Using Negative Control Populations to Assess Unmeasured Confounding and Direct Effects

Squalene Depletion in Skin Following Human Exposure to Ozone under Controlled Chamber Conditions