Simultaneous Multi-Harmonic Imaging of Nanoparticles in Tissues for Increased Selectivity

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Nonlinear frequency conversion processes, such as second-harmonic generation (SHG) and spontaneous parametric down-conversion (SPDC), are essential in many applications, including the generation of entangled photons. It's desirable to enhance these process ...

OBJECTIVE: Malignant pleural mesothelioma (MPM) is a rare disease that has a poor response to conventional therapy. Hyperthermic intrathoracic chemotherapy (HITOC), a treatment combining fever-range hyperthermia with intrapleural cisplatin chemotherapy, ha ...

All-optical poling enables reconfigurable and efficient quasi-phase-matching for second-order parametric frequency conversion in silicon nitride integrated photonics. Here, we report broadly tunable milliwatt-level second-harmonic generation in a small fre ...

Second-harmonic generation allows for coherently bridging distant regions of the optical spectrum, with applications ranging from laser technology to self-referencing of frequency combs. However, accessing the nonlinear response of a medium typically requi ...

Genomic instability enhances cancer progression by favoring clonal diversity, yet uncontrolled replicative stress can lead to mitotic catastrophe and inflammatory responses promoting immune rejection. KRAB-containing zinc finger proteins (KZFPs) are epigen ...

Recent genomic data points to a growing role for somatic mutations altering core histone and linker histone-encoding genes in cancer. However, the prevalence and the clinical and biological implications of histone gene mutations in malignant tumors remain ...

Implicit neural representations (INRs) have recently emerged as a promising alternative to classical discretized representations of signals. Nevertheless, despite their practical success, we still do not understand how INRs represent signals. We propose a ...

Non-invasive and semi-invasive bioimaging is of great interest for the rapid diagnosis and efficient as well as specific treatments of biological systems affecting human health, such as cancer tissue and biofilms. Electrochemical bioimaging is one of the d ...

Diffusion MRI (dMRI) of the developing brain can provide valuable insights into the white matter development. However, slice thickness in fetal dMRI is typically high (i.e., 3-5 mm) to freeze the in-plane motion, which reduces the sensitivity of the dMRI s ...

The Transfer Matrix formalism is ubiquitous when it comes to study wave propagation in various stratified media, applications ranging from Seismology to Quantum Mechanics. A relation between variables at two points in two different layers can be establishe ...

Modern power distribution systems experience a large-scale integration of Converter-Interfaced Distributed Energy Resources (CIDERs). As acknowledged by recent literature, the interaction of individual CIDER components and different CIDERs through the grid ...

Harmonic nanoparticles (HNPs) have emerged as appealing exogenous probes for optical bioimaging due to their distinctive features such as long-term photostability and spectral flexibility, allowing multiphoton excitation in the classical (NIR-I) and extend ...

Quasi-phase-matching has long been a widely used approach in nonlinear photonics, enabling efficient parametric frequency conversions such as second-harmonic generation. However, in silicon photonics the task remains challenging, as materials best suited f ...

Optical imaging probes have played a major role in detecting and monitoring a variety of diseases. In particular, nonlinear optical imaging probes, such as second harmonic generating (SHG) nanoprobes, hold great promise as clinical contrast agents, as they ...

Pancreatic neuroendocrine tumors (PanNET) comprise two molecular subtypes, relatively benign islet tumors (IT) and invasive, metastasis-like primary (MLP) tumors. Until now, the origin of aggressive MLP tumors has been obscure. Herein, using multi-omics ap ...

We demonstrate seeding-enabled all-optical poling of silicon nitride waveguides as short as 5 mm, and account for quasi-phase-matching (QPM) inside the waveguide between the fundamental mode of pump and higher order second-harmonic modes. ...

The invasive behavior of glioblastoma, the most aggressive primary brain tumor, is considered highly relevant for tumor recurrence. However, the invasion zone is difficult to visualize by Magnetic Resonance Imaging (MRI) and is protected by the blood brain ...

Music analysis, in particular harmonic analysis, is concerned with the way pitches are organized in pieces of music, and a range of empirical applications have been developed, for example, for chord recognition or key finding. Naturally, these approaches r ...

In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject da ...

Second-harmonic generation in nonlinear materials can be greatly enhanced by realizing doubly resonant cavities with high quality factors. However, fulfilling such doubly resonant condition in photonic crystal (PhC) slab cavities is a long-standing challen ...

Simultaneous Multi-Harmonic Imaging of Nanoparticles in Tissues for Increased Selectivity

Chattez avec Graph Search

Nonlinear Frequency Conversion in III-Nitride Doubly Resonant Photonic Crystal Cavities

Hyperthermic intrathoracic chemotherapy to control malignant pleural mesothelioma

Tunable photo-induced second-harmonic generation in a mode-engineered silicon nitride microresonator

A chip-scale second-harmonic source via self-injection-locked all-optical poling

KRAB zinc finger proteins link heterochromatin maintenance to replicative stress and inflammation in diffuse large B-cell lymphoma

Pan-cancer atlas of somatic core and linker histone mutations

A Structured Dictionary Perspective on Implicit Neural Representations

Electrochemical imaging of metabolic activity in tissue and biofilms

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Harmonic decomposition of the trace of 1D transfer matrices in layered media

Modelling of AC/DC Interactions of Converter-Interfaced Resources for Harmonic Power-Flow Studies in Microgrids

Gd3+-Functionalized Lithium Niobate Nanoparticles for Dual Multiphoton and Magnetic Resonance Bioimaging

Optically reconfigurable quasi-phase-matching in silicon nitride microresonators

Biodegradable Harmonophores for Targeted High-Resolution In Vivo Tumor Imaging

Cancer Cells Retrace a Stepwise Differentiation Program during Malignant Progression

Seeded Multimode Quasi-Phase-Matching in All-Optically Poled Silicon Nitride Waveguides

Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice

Discovering Tonal Profiles with Latent Dirichlet Allocation

Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

Doubly resonant second-harmonic generation of a vortex beam from a bound state in the continuum