Fluorescence cystoscopy: Perspective in clinical practice and research

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Urinary incontinence (UI) is prevalent and distressing medical condition affecting millions of patients worldwide. Current treatment options for severe cases often involve surgical intervention, such as the implantation of an artificial urinary sphincter ( ...

The present invention relates to a neuromodulation/neurostimulation system (10) for stimulating at least one neuronal circuitry responsible for micturition control in a mammal with bladder disfunction, especially for bladder relaxation and/or for bladder v ...

Neuroprosthetic devices used for the treatment of lower urinary tract dysfunction, such as incontinence or urinary retention, apply a pre-set continuous, open-loop stimulation paradigm, which can cause voiding dysfunctions due to neural adaptation. In the ...

Low urinary tract dysfunctions and symptoms (LUTS) and Urinary incontinence (UI) in particular is a medical condition that affects millions of people worldwide. One of the most promising long term treatments for this condition is the use of an artificial u ...

Retinoblastoma is the most common pediatric eye cancer. It is currently treated with a limited number of drugs, adapted from other pediatric cancer treatments. Drug toxicity and relapse of the disease warrant new therapeutic strategies for these young pati ...

Urinary tract infections (UTIs) are amongst the most common bacterial infections and are the second-most frequent reason for antibiotic prescriptions. Moreover, in about 25% of all treated cases, recurrence of infection occurs. Uropathogenic Escherichia co ...

Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...

Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent reversible neurological disorder characterized by impaired locomotion, cognition and urinary control with ventriculomegaly. Symptoms can be relieved with cerebrospinal fluid drainage, which mak ...

Macrophages sustain tumour progression by facilitating angiogenesis, promoting immunosuppression, and enhancing cancer cell invasion and metastasis. They also modulate tumour response to anti-cancer therapy in pre-clinical models. This knowledge has motiva ...

Ureteral stents are small flexible tubes which are clinically used to restore the urine drainage in presence of obstructions of the ureteral lumen such as tumours, kidney/ureteral stones. The lifetime risk of developing urinary stones is about 20% in men a ...

In patients suffering from underactive bladder (UAB), the contraction of the detrusor muscle has insufficient strength or duration to ensure efficient bladder emptying. Although catheterisation is currently the most effective method to empty the bladder, i ...

Acting as an extracellular matrix protein receptor, alpha(v)beta(3) integrin becomes an appealing target for photodynamic therapy of bladder cancer. Here, specific alpha(v)beta(3)-integrin-targeting porphyrinato-gadolinium complexes (Gd-PEG-R-n) are demons ...

Current treatments for underactive bladder (UAB) have negative side effects, such as urinary tract infections, mainly because devices used for bladder emptying are in direct contact with urine (e.g. permanent or intermittent catheterisation). Moreover, mos ...

Neuromodulation, the use of electrical interfaces to alter neuronal activity, has been successful as a treatment approach in several neurological disorders, including deep brain stimulation for Parkinson's disease and epidural spinal stimulation for chroni ...

Introduction: Many studies have shown that electrostimulation of the cavernosal nerve can induce and maintain penile erection. Based on these discoveries, neurostimulation to activate the erectile response has been considered a potential solution to treat ...

Clinical success of bladder reconstructive procedures could be promoted by the availability of functional biomaterials. In this study, we have developed a multi-layered scaffold consisting of a bioactive fibrin layer laminated between two collagen sheets a ...

This paper deals with the sense of represent- ing both a new domain as Digital Humanities and its community. Based on a case study, where a set of visualizations was used to represent the community attending the international Digital Humanities conference ...

Efforts to understand spinal cord injury (SCI) and other complex neurotrauma disorders at the pre-clinical level have shown progress in recent years. However, successful translation of basic research into clinical practice has been slow, partly because of ...

Fluorescence cystoscopy enhances detection of early bladder cancer. Water used to inflate the bladder during the procedure rapidly contains urine, which may contain fluorochromes. This frequently degrades fluorescence images. Samples of bladder washout flu ...

Background: Hypospadias and urethral strictures are conditions requiring additional tissue for reconstruction. Due to a limited source of tissue, autologous skin and oral mucosa are frequently used. However, long-term follow-up studies demonstrated signifi ...

Fluorescence cystoscopy: Perspective in clinical practice and research

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An artificial urinary sphincter based on dielectric elastomer technology

System for micturition control in a mammal with bladder disfunction

Decoding bladder state from pudendal intraneural signals in pigs

Mechanical Characterisation of Porcine Urethra: Non Linear Constitutive Models and Experimental Approach

Translational screening platform to evaluate chemotherapy in combination with focal therapy for retinoblastoma

Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

Neural circuits of idiopathic Normal Pressure Hydrocephalus: A perspective review of brain connectivity and symptoms meta-analysis

Biology and therapeutic targeting of tumour-associated macrophages

Development of a biologically inspired in-vitro platform for long-term assessment of commercial and innovative ureteral stents

Impedance pumping as a non-invasive treatment for underactive bladder? An ex-vivo proof-of-concept-study in porcine bladders

Bladder Cancer Photodynamic Therapeutic Agent with Off-On Magnetic Resonance Imaging Enhancement

Urine-Contactless Device to Empty Bladders: an Ex-Vivo Proof-of-Concept Study in Porcine Bladders

Neuromodulation in the restoration of function after spinal cord injury

Novel Concept Enabling an Old Idea: A Flexible Electrode Array to Treat Neurogenic Erectile Dysfunction

IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering

Representing the Digital Humanities Community: Unveiling The Social Network Visualization of an International Conference

Development of a Database for Translational Spinal Cord Injury Research

Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

Is There a Need for Smooth Muscle Cell Transplantation in Urethral Reconstruction?