While the recent theory of compressed sensing provides an opportunity to overcome the Nyquist limit in recovering sparse signals, a solution approach usually takes the form of an inverse problem of an unknown signal, which is crucially dependent on specifi ...
We propose a new, cost-efficient method for computing back projections in parallel-ray X-ray CT. Forward and back projections are the basis of almost all X-ray CT reconstruction methods, but computing these accurately is costly. In the special case of para ...
Developmental Hedgehog (Hh) signaling is found deregulated in a broad spectrum of human malignancies and, thus, is an attractive target for cancer therapy. Currently available Hh inhibitors have shown the rapid occurrence of drug resistance, due to altered ...
Precise regulation of the Notch signaling pathway is crucial, as increases or deficiencies in signaling are associated with diseases, including a wide range of cancers. Recent studies have demonstrated that monoclonal antibodies that bind and stabilize the ...
Proteomic technologies using MS offer new perspectives in circadian biology, in particular the possibility to study PTMs. To date, only very few studies have been carried out to decipher the rhythmicity of protein expression in mammals with large-scale pro ...
Foundations of signal processing are heavily based on Shannon's sampling theorem for acquisition, representation and reconstruction. This theorem states that signals should not contain frequency components higher than the Nyquist rate, which is half of the ...