Publications associées à Does chronic nicotine consumption influence visual backward masking in schizophrenia and schizotypy?

The neighborhood environment and its association with the spatio-temporal footprint of tobacco consumption and changes in smoking-related behaviors in a Swiss urban area

Stéphane Joost, David Nicolas De Ridder, Idris Guessous

This study aimed to evaluate the association of the neighborhood environment with the spatio-temporal dependence of tobacco consumption and changes in smoking-related behaviors in a Swiss urban area. ...

ELSEVIER SCI LTD2022

Associations between urinary biomarkers of oxidative stress and biomarkers of tobacco smoke exposure in smokers

Dominique Grandjean, Florian Frédéric Vincent Breider, Nicolas Sambiagio

Oxidative stress can contribute to the development of diseases, and may originate from exposures to toxicants commonly found in air pollution and cigarette smoke such as polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs). Yet, as ...

Elsevier2022

Opposite effects of stress on effortful motivation in high and low anxiety are mediated by CRHR1 in the VTA

Maria del Carmen Sandi Perez, Olivia Zanoletti, Jocelin Grosse, Marie-Isabelle Guillot de Suduiraut, Ioannis Zalachoras, Simone Astori, Mandy Meijer

Individuals frequently differ in their behavioral and cognitive responses to stress. However, whether motivation is differently affected by acute stress in different individuals remains to be established. By exploiting natural variation in trait anxiety in ...

2022

The shine-through paradigm and the schizophrenia spectrum: a summary

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Simona Adele Garobbio, Janir Nuno Ramos Antunes Da Cruz

In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...

2021

Electrophysiological correlates of visual backward masking in patients with bipolar disorder

Michael Herzog, Maya Roinishvili, Ophélie Gladys Favrod, Simona Adele Garobbio, Janir Nuno Ramos Antunes Da Cruz

In visual backward masking (VBM), a target is followed by a mask that decreases target discriminability. Schizophrenia patients (SZ) show strong and reproducible masking impairments, which are associated with reduced EEG amplitudes. Patients with bipolar d ...

2021

Electrochemical determination of nicotine in smokers' sweat

Sandro Carrara, Tugba Kilic

In this work, we report the demonstration of the capability of electrochemical sensors to provide measurements directly on the sweat of volunteers to successfully discriminate heavy smokers by light ones. Since its importance as pharmaceutical treatment-ag ...

ELSEVIER2020

Electrophysiological correlates of visual backward masking in the schizophrenia continuum

Ophélie Gladys Favrod

In visual backward masking (VBM), a target is followed by a mask. Over the past decade, a VBM task, called the Shine-Through paradigm (ST), has been shown to be a very sensitive endophenotype of schizophrenia. In the present thesis, the electrophysiologica ...

EPFL2019

Public smoking ban and socioeconomic inequalities in smoking prevalence and cessation: a cross-sectional population-based study in Geneva, Switzerland (1995–2014)

Stéphane Joost, Idris Guessous

Introduction Smoking bans were suggested to reduce smoking prevalence and increase quit ratio but their equity impact remains unclear. We aimed to characterise the socioeconomic status (SES)-related inequalities in smoking prevalence and quit ratio before ...

2018

Visual masking deficits in schizophrenia: A view into the genetics of the disease through an endophenotype

Michael Herzog, Maya Roinishvili, Jacques Fellay, Flavia Aurelia Shoko Hodel

Schizophrenia is a chronic disorder determined by a complex mix of genetic and environmental factors. To better understand the contributions of human genetic variation to schizophrenia, we performed a genome-wide association study of a validated endophenot ...

2018

Frequent walkers: from healthy individual behaviours to sustainable mobility futures

Derek Pierre Christie

Walking is often taken for granted or considered as an ancillary activity. Little is known about the distribution of walking in contemporary populations, and even less about the few people who walk for an hour or more in public space on most days of the we ...

EPFL2018

Inhaling xenon ameliorates l -dopa-induced dyskinesia in experimental parkinsonism

Tomislav Milekovic, Grégoire Courtine, Eduardo Martin Moraud, Shiqi Sun

Parkinson's disease motor symptoms are treated with levodopa, but long‐term treatment leads to disabling dyskinesia. Altered synaptic transmission and maladaptive plasticity of corticostriatal glutamatergic projections play a critical role in the pathophys ...

2018

Increased Myeloid Cell Production and Lung Bacterial Clearance in Mice Exposed to Cigarette Smoke

Alessandra Piersigilli

Pneumonia is a leading cause of hospitalization in patients with chronic obstructive pulmonary disease (COPD). Although most patients with COPD are smokers, the effects of cigarette smoke exposure on clearance of lung bacterial pathogens and on immune and ...

Amer Thoracic Soc2016

Visual backward masking deficits in schizotypy are observed in late but not early onset nicotine smokers

Michael Herzog, Guillaume Sierro, Christine Mohr, Géraldine Beaud

Visual backward masking (VBM) is a potential endophenotype for schizophrenia. Relative VBM deficits were also observed in high as compared to low scorers in one schizotypal subdimension (cognitive disorganisation, CogDis; Cappe et al., 2012). VBM deficits ...

2014

Small effects of smoking on visual spatiotemporal processing

Michael Herzog

Nicotine is an important stimulant that is involved in modulating many neuronal processes, including those related to vision. Nicotine is also thought to play a key role in schizophrenia: A genetic variation of the cholinergic nicotine receptor gene, alpha ...

Nature Publishing Group2014

General developmental health in the VPA-rat model of autism

Henry Markram, Kamila Markram, Mônica Regina Favre, Georges Khazen

Autism is a neurodevelopmental condition diagnosed by impaired social interaction, abnormal communication and, stereotyped behaviors. While post-mortem and imaging studies have provided good insights into the neurobiological symptomology of autism, animal ...

Frontiers Research Foundation2013

Hyper-emotional neurophysiology in a rat model of autism

Mônica Regina Favre

Autism is a pervasive neurodevelopmental disorder of unknown etiology, characterized by a spectrum of symptoms of social impairment, abnormal communication, and unusual restricted, inflexible behaviors. Patients also frequently present various levels of se ...

EPFL2013

Patients with functional psychoses show similar visual backward masking deficits

Michael Herzog, Maya Roinishvili

Recent genetic, behavioral, and clinical studies suggest that functional psychoses (schizophrenia, bipolar disorder, schizoaffective disorder), previously thought to be distinct from each other, may belong to one continuum. The shine-through masking paradi ...

Elsevier2012

Backward masking reveals different visual processing of schizophrenic and depressive patients

Michael Herzog, Maya Roinishvili

Visual backward masking is a very sensitive tool for studying early visual processing deficits and a reliable endophenotype of schizophrenia. Mental diseases strongly overlap in many aspects, for example, in psychopathology, cognition, and genetics. Here, ...

Pion Ltd.2012

Deteriorated visual backward masking in the shine-through effect in adolescents with psychosis

Michael Herzog

Visual backward masking is a reliable and widely used tool in schizophrenia research. Whereas many studies have shown masking deficits in adult patients, there are only very few studies with adolescents with psychosis-and with controversial results. Maskin ...

Taylor & Francis2009