Publications associées à Genomic screening of 16 UK native bat species through conservationist networks uncovers coronaviruses with zoonotic potential

Publications associées (5)

Structure-Activity Relationship Studies of Glycosaminoglycan Mimetic Macrocycles Against Herpes

Cynthia Paloma Aigroz, Hien Tran Thi, Deepika Sardana, Anita Zucchi, Francesco Stellacci, Paulo Henrique Jacob Silva, Melis Özkan, Sujeet Pawar

The herpes simplex virus (HSV) is associated with serious conditions, such as encephalitis and blindness, and its infection is closely linked to significant vascular complications and coagulation issues, particularly in individuals with compromised immune ...

AMER CHEMICAL SOC2025

A Synthetic Multivalent Lipopeptide Derived from Pam3CSK4 with Irreversible Influenza Inhibition and Immuno-Stimulating Effects

Francesco Stellacci, Bruno Emanuel Ferreira De Sousa Correia, Li Tang, Quy Ong Khac, Pablo Gainza Cirauqui, Lixia Wei, Armand Kurum, Yong Zhu, Francesca Olgiati

The activation of the host adaptive immune system is crucial for eliminating viruses. However, influenza infection often suppresses the innate immune response that precedes adaptive immunity, and the adaptive immune responses are typically delayed. Dendrit ...

Wiley-V C H Verlag Gmbh2024

Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys

Didier Trono, Henning Paul-Julius Stahlberg, Priscilla Turelli, Florence Pojer, Dongchun Ni, Kelvin Ka Ching Lau, Charlène Mireille Raymonde Raclot

The SARS-CoV-2 Omicron variant has very high levels of transmission, is resistant to neutralization by authorized therapeutic human monoclonal antibodies (mAb) and is less sensitive to vaccine-mediated immunity. To provide additional therapies against Omic ...

2022

An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles

Francesco Stellacci, Matteo Gasbarri

Minimizing the spread of viruses in the environment is the first defence line when fighting outbreaks and pandemics, but the current COVID-19 pandemic demonstrates how difficult this is on a global scale, particularly in a sustainable and environmentally f ...

Nature Research2021

Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment

Jacques Fellay, Christian Axel Wandall Thorball, Alessandro Borghesi

Background: The primary hurdle for the eradication of HIV-1 is the establishment of a latent viral reservoir early after primary infection. Here, we investigated the potential influence of human genetic variation on the HIV-1 reservoir size and its decay r ...

LIPPINCOTT WILLIAMS & WILKINS2020