Publications associées à Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth

Publications associées (6)

Cerebellar dysfunction in frontotemporal dementia: intra-cerebellar pathology and cerebellar network degeneration

Background: Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) share overlapping clinical, genetic, and neuroimaging features; a spectrum of conditions commonly referred to as the ALS-FTD continuum. The majority of imaging studies focus ...

2025

An integrative computational modeling approach for Drosophila motor control

Pembe Gizem Ozdil

Animal motor control arises from the intricate interplay between neural circuits, biomechanics, and sensory feedback. Deciphering how these components interact is essential for uncovering the fundamental principles of movement generation. This dissertation ...

EPFL2025

Food perception promotes phosphorylation of MFFS131 and mitochondrial fragmentation in liver

Suliana Manley, Tatjana Isabelle Kleele

All rights reserved.Liver mitochondria play a central role in metabolic adaptations to changing nutritional states, yet their dynamic regulation upon anticipated changes in nutrient availability has remained unaddressed. Here, we found that sensory food pe ...

American Association for the Advancement of Science2024

RNA Expression of MMP12 Is Strongly Associated with Inflammatory Bowel Disease and Is Regulated by Metabolic Pathways in RAW 264.7 Macrophages

Luis Francisco Lorenzo Martin

Macrophage metalloelastase or matrix metalloproteinase-12 (MMP12) is a macrophage-specific proteolytic enzyme involved in the physiopathology of many inflammatory diseases, including inflammatory bowel disease. Although previously published data suggested ...

MDPI2024

Connectomic reconstruction of a female Drosophila ventral nerve cord

Jasper Taylor Phelps

A deep understanding of how the brain controls behaviour requires mapping neural circuits down to the muscles that they control. Here, we apply automated tools to segment neurons and identify synapses in an electron microscopy dataset of an adult female Dr ...

NATURE PORTFOLIO2024

Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies

Pierre Vogel, Somi Reddy Majjigapu, Jianfei Bai

Targeting cancer cells that are highly dependent on the nicotinamide adenine dinucleotide (NAD+) metabolite is a promising therapeutic strategy. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme catalyzing NAD(+) production. Despit ...

MDPI2023