Arylsilylation of Electron-Deficient Alkenes via Cooperative Photoredox and Nickel Catalysis

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Herein we report a mild synthesis of propargyl silanes from terminal alkynes. We exploit a bromonaphthyl-substituted silane as a silylmethyl electrophile surrogate, which participates in a Sonogashira reaction after an aryl-to-alkyl Pd-migration. Twenty-se ...

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The chemoenzymatic dynamic kinetic resolution of beta-amino esters is established after detailed evaluation of metal-based heterogeneous catalysts for racemization and enzyme catalysts for kinetic resolution. Several heterogeneous palladium catalysts prove ...

Arylsilylation of Electron-Deficient Alkenes via Cooperative Photoredox and Nickel Catalysis

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