Genetic Association of Recovery from Eating Disorders: The Role of GABA Receptor SNPs

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Background The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by host genetic variation. In the framework of the Milieu Interieur Consortium, a total ...

In everyday life, eating follows patterns and occurs in context. We present an approach to discover daily eating routines of a population following a multidimensional representation of eating episodes, using data collected with the Bites'n'Bits smartphone ...

Social dominance can be attained through social competitions. Recent work in both humans and rodents has identified trait anxiety as a crucial predictor of social competitiveness. In addition, the anxiolytic GABAA positive modulator, diazepam, injected eit ...

Medium-chain triglycerides (MCT) are emerging as unique dietary supplements that are potentially relevant for the amelioration of brain dysfunctions. MCT are converted into ketones and free medium chain fatty acids that, in the brain, are highly effective ...

Background Inherited optic neuropathies (IONs) cover a spectrum of clinically and genetically heterogenic conditions. Genetic evaluation of patients with IONs may enable their better clinico-diagnostic assessment and management of the disease. The aim of t ...

Schizophrenia is a complex and devastating mental disorder that influences how one behaves, feels, and thinks. It affects a little less than 1 % of the world population and it is understood to be partly genetically mediated. Several genetic risk factors of ...

The impressive technological advances in genomic analysis and the significant drop in the cost of genome sequencing are paving the way to a variety of revolutionary applications in modern healthcare. In particular, the increasing understanding of the human ...

Studying the genetic basis of gene expression and chromatin organization is key to characterizing the effect of genetic variability on the function and structure of the human genome. Here we unravel how genetic variation perturbs gene regulation using a da ...

In this thesis, we deal with one of the facets of the statistical detection problem. We study a particular type of alternative, the mixture model. We consider testing where the null hypothesis corresponds to the absence of a signal, represented by some kno ...

Genetic Association of Recovery from Eating Disorders: The Role of GABA Receptor SNPs

Chattez avec Graph Search

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals

Discovering Eating Routines in Context with a Smartphone App

GABA A receptors in the ventral tegmental area control the outcome of a social competition in rats

Medium chain triglyceride diet reduces anxiety-like behaviors and enhances social competitiveness in rats

Analysis of Inherited Optic Neuropathies

EEG signatures of schizophrenia: visual backward masking and microstates

Privacy-Enhancing Technologies for Medical and Genomic Data: From Theory to Practice

Chromatin three-dimensional interactions mediate genetic effects on gene expression

The detection of two-component mixture alternatives : Theory and methods