Genetic variation plays a crucial role in human disease susceptibility and molecular pathophysiology. This thesis explores genetic determinants of disease using advanced computational approaches, including statistical modeling, network analysis, and deep l ...
Functional connectivity patterns in the human brain, like the friction ridges of a fingerprint, can uniquely identify individuals. Does this “brain fingerprint” remain distinct even during Alzheimer’s disease (AD)? Using fMRI data from healthy and patholog ...
The first Swiss national dietary survey (MenuCH) was used to screen disease burdens and greenhouse gas emissions (GHG) of Swiss diets (vegan, vegetarian, gluten-free, slimming), with a focus on gender and education level. The Health Nutritional Index (HENI ...
Tumor-initiating cells with stem cell properties are believed to sustain the growth of gliomas, but proposed markers such as CD133 cannot be used to identify these cells with sufficient specificity. We report an alternative isolation method purely based on ...