Cells in 3D matrices under interstitial flow: Effects of extracellular matrix alignment on cell shear stress and drag forces

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Localized sources of morphogens, called signalling centres, play a fundamental role in coordinating tissue growth and cell fate specification during organogenesis. However, how these signalling centres are established in tissues during embryonic developmen ...

Reinforced concrete flat slabs consist of a continuous, thin concrete plate that rests on a grid of columns. The supporting surface of the columns is very small compared to the floor plan dimensions, leading to concentrations of shear forces near the colum ...

We consider fluid flows, governed by the Navier-Stokes equations, subject to a steady symmetry-breaking bifurcation and forced by a weak noise acting on a slow timescale. By generalizing the multiple-scale weakly nonlinear expansion technique employed in t ...

This work introduces a new methodology to predict the fatigue life of viscoelastic materials by considering the creep effect on fatigue behavior under the concurrent effects of stress level, stress ratio, and temperature. The model established based on the ...

BackgroundImpaired cerebrospinal fluid (CSF) dynamics is involved in the pathophysiology of neurodegenerative diseases of the central nervous system and the optic nerve (ON), including Alzheimer's and Parkinson's disease, as well as frontotemporal dementia ...

Earthquakes i.e. frictional ruptures, are commonly described by singular solutions of shear crack motions. These solutions assume a square root singularity order around the rupture tip and a constant shear stress value behind it, implying scale-independent ...

We study the flow stability and spatiotemporal spectral dynamics of cellulose nanocrystal (CNC) suspensions in a custom Taylor-Couette flow cell using the intrinsic shear induced birefringence and liquid crystalline properties of CNC suspensions for flow v ...

Fiber-polymer composites consist of a polymer matrix and reinforcing fibers made of various materials. These composites exhibit exceptional properties, such as a high strength-to-weight ratio and excellent corrosion resistance, which has led to their incre ...

The goal of this work is to use anisotropic adaptive finite elements for the numerical simulation of aluminium electrolysis. The anisotropic adaptive criteria are based on a posteriori error estimates derived for simplified problems. First, we consider an ...

The different receptors in human skin show not only diversity in the stimuli to which they respond, but also variable sensitivity and directionality. This is often determined by their location or morphology, and can play an important role in filtering or a ...

We update the publicly available weak lensing shear measurement algorithm pyRRG for the JWST, and apply it to UNCOVER DR1 imaging of galaxy cluster Abell 2744. At short wavelengths (

Atomic force microscopy (AFM) is a widely used imaging tool for obtaining a variety of information for a range of samples. Although it was initially intended to serve as a method of observing very flat solid surfaces, its use expanded into several other fi ...

Organoids, miniature tissues generated from self-organizing stem cells within three-dimensional (3D) extracellular matrices (ECM), have opened up exciting possibilities for in vitro studies of complex physiological processes. A key factor in the success of ...

In this paper, we consider experimental data available for graphene-based nanolubricants to evaluate their convective heat transfer performance by means of computational fluid dynamics (CFD) simulations. Single-phase models with temperature-dependent prope ...

Brillouin scattering in gas shows unmatched gain properties in hollow-core optical fibers filled at high pressure. Here, the gain characteristics are studied for two common gases, namely, N2 and CO2, which show distinct features and are compared to expecte ...

ObjectiveWall shear stress (WSS) and its derived spatiotemporal parameters have proven to play a major role on intracranial aneurysms (IAs) growth and rupture. This study aims to demonstrate how ultra-high field (UHF) 7 T phase contrast magnetic resonance ...

In this research, the flow features around a spur dike located in a 90˚ sharp channel bend have been studied experimentally in detail. Results showed that the effects of the spur dike on upstream sections increased by increasing α (spur dike location from ...

We investigate the fluid-driven growth of a shear crack along a frictional discontinuity and its transition to hydraulic fracturing (sometimes referred to as hydraulic jacking) under plane-strain conditions. We focus on the case of a constant friction coef ...

The dynamic of fine sediment in rivers is closely related to the interactions between fine particles, the riverbed and the flow conditions. The accumulation of fine sediment in the riverbed reduces vertical water exchanges and can have detrimental effects ...

Superionics are fascinating materials displaying both solid- and liquid-like characteristics: as solids, they respond elastically to shear stress; as liquids, they display fast-ion diffusion at normal conditions. In addition to such scientific interest, su ...

Cells in 3D matrices under interstitial flow: Effects of extracellular matrix alignment on cell shear stress and drag forces

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Proliferation-driven mechanical compression induces signalling centre formation during mammalian organ development

Shear and steel-fibre reinforcement for the punching resistance of flat slabs at internal and edge columns

Noise-induced transitions past the onset of a steady symmetry-breaking bifurcation: The case of the sudden expansion

A novel fatigue life prediction methodology based on energy dissipation in viscoelastic materials, synergistic effects of stress level, stress ratio, and temperature

Large-scale in-silico analysis of CSF dynamics within the subarachnoid space of the optic nerve

Frictional weakening leads to unconventional singularities during dynamic rupture propagation

Painting Taylor vortices with cellulose nanocrystals: Suspension flow supercritical spectral dynamics

Two-dimensional quasi-static delamination in composite laminates under Mode-I and Mode-II conditions

Adaptive Finite Elements with Large Aspect Ratio. Application to Aluminium Electrolysis

Morphological and Material Programability of a Hall-Effect Based Soft Tactile Sensors

Weak gravitational lensing measurements of Abell 2744 using JWST and shear measurement algorithm pyRRG-JWST

Advancements in Nanomechanical Characterization and Biomolecular Imaging with Atomic force Microscopy

Engineering hydrogel microenvironments for epithelial organoid culture

Computational fluid dynamics simulations of the heat transfer properties of graphene-based nanolubricants and application to hydrodynamic lubrication

Study of backward Brillouin scattering in gas-filled anti-resonant fibers

Near-wall hemodynamic parameters quantification in in vitro intracranial aneurysms with 7 T PC-MRI

The effects of a spur dike location in a 90° sharp channel bend on flow field: Focus on anisotropy degree and anisotropy nature

Shearing and opening of a pre-existing discontinuity in response to fluid injection

Influence of the shear stress on fine sediment exchanges with the substrate using UVP measurements

Solids that are also liquids: elastic tensors of superionic materials