Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood

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Cis-genetic effects are key determinants of transcriptional divergence in discrete tissues and cell types. However, how cis- and trans-effects act across continuous trajectories of cellular differentiation in vivo is poorly understood. Here, we quantify al ...

The need of full transposition of the current carrying elements (strands) in large cables is frequently retained as top design criterion for conductors operating in pulsed mode. However, when the transposition error, i.e., the inductance difference among t ...

A user’s benefit from the energy stored in a battery over its lifetime depends on the time-varying characteristics of the battery, which are in turn affected by the chosen usage behavior. Both the capacity shrinkage and the number of lifetime cycles are st ...

Cyclic peptides are fascinating molecules abundantly found in nature and exploited as molecular format for drug development as well as other applications, ranging from research tools to food additives. Advances in peptide technologies made over many years ...

In an era where portable electronic devices are indispensable for a wide range of activities, the need for displays that provide both long-lasting battery life and excellent visibility in different lighting conditions is increasingly important. Emissive di ...

Group testing is a technique that can reduce the number of tests needed to identify infected members in a population, by pooling together multiple diagnostic samples. Despite the variety and importance of prior results, traditional work on group testing ha ...

Long-term consumption of lipid-rich foods can contribute to common metabolic diseases and systemic low-grade inflammation. However, dietary responses and the development of non-communicable diseases are shaped by genetic factors and gene-by-environment int ...

Masonry buildings form building aggregates around the world in historical centers, which developed as the layout of the city or village densified. In these aggregates, adjacent buildings can share structural walls, connected at the interfaces by interlocki ...

The plastic deformation of small-scale face-centered cubic metals exhibits intermittent slip burst events that appear on stress-strain curves as sudden strain jumps and/or load drops. These events are generally attributed to the avalanche-like cooperative ...

Molybdenum cofactor deficiency type B (MOCODB; #252160) is an autosomal recessive metabolic disorder that has only been described in 37 affected patients. In this report, we describe the presence of an in-frame homozygous variant (c.471_477delTTTAAAAinsG) ...

The terminology of neurological disorders encompasses a range of serious illnesses (e.g., epilepsy, Alzheimer's disease) leading to morbidity, disability, and stigma. Epilepsy alone affects over 50 million people worldwide, and these figures are rising as ...

Genetic and cellular drivers of the cellular uptake of SARS-CoV-2 can be screened at high throughput via droplet microfluidics and size-exclusion methods for the analysis of the formation of fusions between cells expressing the virus's spike protein and ce ...

Connectivity between the hyporheic zone and the flow is essential for the development of benthos and the reproductive success of spawning fish. The infiltration of fine sediment leads to clogging of the riverbed, reducing porosity and vertical water exchan ...

Type 2 diabetes mellitus (T2DM) can be multifactorial where both genetics and environmental factors play a role. We aimed to investigate the use of polygenic risk scores (PRS) in the prediction of pre-transplant T2DM and post-transplant diabetes mellitus ( ...

Krüppel-associated box (KRAB) domain-containing zinc finger proteins (KZFPs) are one of the largest groups of transcription factors encoded by tetrapods, with 378 members in human alone. KZFP genes are often grouped in clusters reflecting amplification by ...

Predictive health assessment is of vital importance for smarter battery management to ensure optimal and safe operations and thus make the most use of battery life. This paper proposes a general framework for battery aging prognostics in order to provide t ...

Continuous dendrites growth, as well as corrosion and side reactions of Zn metal anode seriously hinder the development of aqueous zinc ion batteries. To address these issues, oleic acid (OA) is dispersed into a 2 M ZnSO4 solution to form a novel colloidal ...

DNA methylation (DNAm) is one of the most frequently studied epigenetic mechanisms facilitating the interplay of genomic and environmental factors, which can contribute to externalizing behaviours and related psychiatric disorders. Previous epigenome-wide ...

Herein, a fluoropolymer bifunctional solid membrane interface (SMI) for an aqueous Al-air battery is proposed, which inhibits anodic self-corrosion, while concurrently reducing the accumulation of undesirable by-products. A battery using the SMI exhibits a ...

The standard physiological model has serious problems accounting for many aspects of vision, particularly when stimulus configurations become slightly more complex than the ones classically used, e.g., configurations of Gabors rather than only one or a few ...

Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood

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The dynamic genetic determinants of increased transcriptional divergence in spermatids

Performance Comparison of Cables With Partial Transposition

Optimal Depth of Discharge for Electric Batteries with Robust Capacity-Shrinkage Estimator

Cyclic Peptides for Drug Development

MEMS-based Tunable Metasurface for Reflective Display Applications

Community-Aware Group Testing

Identifying genetic and dietary modulators of metabolic disorders using systems genetics

Seismic Testing of Adjacent Interacting Masonry Structures

On the slip burst amplitude cutoff in dislocation-rich microcrystals

Live Birth of a Healthy Child in a Couple with Identical mtDNA Carrying a Pathogenic c.471_477delTTTAAAAinsG Variant in the MOCS2 Gene

Real-time Personalized Monitoring of Neurological Disorders on Wearable Systems

Screening for drivers of SARS-CoV-2 uptake

Impact of substrate clogging on vertical connectivity

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Genetic features and genomic targets of human KRAB-zinc finger proteins

Predictive health assessment for lithium-ion batteries with probabilistic degradation prediction and accelerating aging detection

A colloidal aqueous electrolyte modulated by oleic acid for durable zinc metal anode

Epigenome-wide DNA methylation in externalizing behaviours: A review and combined analysis

A fluoropolymer bifunctional solid membrane interface for improving the discharge duration in aqueous Al-air batteries

Specific Gestalt principles cannot explain (un)crowding