A Network Based Kernel Density Estimator Applied to Barcelona Economic Activities

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Water distribution systems (WDSs) are complex networks with numerous interconnected junctions and pipes. The robustness and reliability of these systems are critically dependent on their network structure, necessitating detailed analysis for proactive leak ...

Native reactive electrophile species (RES) such as 4-hydroxynonenal (HNE) act as cellular signals through covalent modification of kinetically-privileged electrophile sensor proteins. Research efforts in the field focus mainly on identifying these sensor p ...

Cells of two molecular genetic types of breast cancer-hormone-dependent breast cancer (ZR-75 cell line) and triple-negative breast cancer (BT-20 cell line)-were studied using atomic force microscopy and an optical nanomotion detection method. Using the Pea ...

Recent studies suggested that long-lived photooxidants (LLPO), which are reactive intermediates formed during irradiation of dissolved organic matter (DOM), may consist of phenoxyl radicals derived from phenolic moieties of the DOM. Besides the well-studie ...

Discrete domes are doubly curved structures comprising a network of beam-like elements. We study the mechanics of discrete domes made of ribbons woven in a pentagonal triaxial pattern. Experiments and finite element simulations are performed to characteriz ...

The magnetic propertiesof transition-metal ions aregenerallydescribed by the atomic spins of the ions and their exchange coupling.The orbital moment, usually largely quenched due the ligand field,is then seen as a perturbation. In such a scheme, S = 1/2 io ...

Viruses initiate invasion by binding to cell surface glycoproteins. Materials mimicking the carbohydrate motifs of these glycoproteins, such as heparan sulfate (HS) and sialic acid (SA) can block viral attachment and inhibit the infection. Multivalent disp ...

The presence of competing events, such as death, makes it challenging to define causal effects on recurrent outcomes. In this thesis, I formalize causal inference for recurrent events, with and without competing events. I define several causal estimands an ...

Background: The development of therapeutics for Parkinson's disease (PD) requires the establishment of biomarker assays to enable stratifying patients, monitoring disease progression, and assessing target engagement. Attempts to develop diagnostic assays b ...

Near-surface wind is difficult to estimate using global numerical weather and climate models, because airflow is strongly modified by underlying topography, especially that of a country such as Switzerland. In this article, we use a statistical approach ba ...

We construct (modified) scattering operators for the Vlasov–Poisson system in three dimensions, mapping small asymptotic dynamics as t→−∞ to asymptotic dynamics as t→+∞. The main novelty is the construction of modified wave operators, but we also obtain a ...

In competing event settings, a counterfactual contrast of cause-specific cumulative incidences quantifies the total causal effect of a treatment on the event of interest. However, effects of treatment on the competing event may indirectly contribute to thi ...

Modelling and analysis of biological systems is crucial in order to quantitatively explain and predict their behaviour. The importance of modelling in systems biology becomes even more evident when tackling complex, large systems. Approaches that rely on ...

In the Wendelstein 7-X (W7-X) stellarator, the vacuum rotational transform, ι, has a flat radial profile and does not cross any major rational resonance. Nevertheless, during plasma operation the ι‐profile can be strongly modified by electron cyclotron cur ...

Here we report the design of a disposable single-drop voltammetric sensor for the quantitative determination of antipsy-chotic drug trifluoperazine (TFP). The sensor was build using inkjet-printed carbon nanotube (CNT) electrodes which were modified with d ...

Assays focusing on emerging biological phenomena in an animal's life can be performed during embryogenesis. While the embryo of Caenorhabditis elegans has been extensively studied, its biomechanical properties are largely unknown. Here, we demonstrate that ...

The fast-paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen-oriented security, recombinantDNAresearch, and broa ...

Testing for equality of two high-dimensional distributions is a challenging problem, and this becomes even more challenging when the sample size is small. Over the last few decades, several graph-based two-sample tests have been proposed in the literature, ...

Background Alzheimer's disease (AD) is a complex disorder caused by a combination of genetic and non-genetic risk factors. In addition, an increasing evidence suggests that epigenetic mechanisms also accompany AD. Genetic and epigenetic factors are not ind ...

An increasing number of studies are using landscape genomics to investigate local adaptation in wild and domestic populations. The implementation of this approach requires the sampling phase to consider the complexity of environmental settings and the burd ...

A Network Based Kernel Density Estimator Applied to Barcelona Economic Activities

Chattez avec Graph Search

Towards an Understanding of Hydraulic Sensitivity: Graph Theory Contributions to Water Distribution Analysis

Towards Uncovering the Mechanisms of Electrophile Sensing and Signaling

Mechanical Properties and Nanomotion of BT-20 and ZR-75 Breast Cancer Cells Studied by Atomic Force Microscopy and Optical Nanomotion Detection Method

Impact of chlorination and ozonation of dissolved organic matter on its photo-induced production of long-lived photooxidants and excited triplet states

Indentation and stability of woven domes

Large Orbital Moment of Two Coupled Spin-Half Co Ions in a Complex on Gold

Multivalent Virucidal Antivirals: Synthesis, Mechanisms of Action, and Immune-stimulating Effects

Interventionist estimands in event history analysis

Comparative Analysis of Total Alpha-Synuclein (alpha SYN) Immunoassays Reveals That They Do Not Capture the Diversity of Modified alpha SYN Proteoforms

Downscaling of Historical Wind Fields over Switzerland Using Generative Adversarial Networks

Scattering Map for the Vlasov–Poisson System

A generalized theory of separable effects in competing event settings

Modelling the Intracellular Environment under Uncertainty, from Post-translational Modification to Metabolic Networks

Model for current drive induced crash cycles in W7-X

Inkjet-Printed Carbon Nanotube Electrodes Modified with Dimer-captosuccinic Acid-Capped Fe3O4 Nanoparticles on Reduced Graphene Oxide Nanosheets for Single-Drop Determination of Trifluoperazine

Force microscopy of the Caenorhabditis elegans embryonic eggshell

Building biosecurity for synthetic biology

On some graph-based two-sample tests for high dimension, low sample size data

Comprehensive analysis of PM20D1 QTL in Alzheimer's disease

Sampling strategy optimization to increase statistical power in landscape genomics: a simulation-based approach