Catechol Containing Polyelectrolyte Complex Nanoparticles as Local Drug Delivery System for Bortezomib at Bone Substitute Materials

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In aqueous solutions, a charged surface causes the redistribution of nearby ions. The ion layers formed are known as the electrical double layer (EDL), and are widespread in many systems involving electrochemistry, colloidal science, biomedicine, and energ ...

Witness encryption is a cryptographic primitive which encrypts a message under an instance of an NP language and decrypts the ciphertext using a witness associated with that instance. In the current state of the art, most of the witness encryption construc ...

To reduce the CO2 footprint of construction materials, concrete producers blend their cement with Supplementary Cementitious Materials (SCMs). SCMs such as fly ash or blast furnace slag are mostly the byproducts of other industries. And while SCMs are chos ...

Photocatalytic applications play an essential role in the search for alternative energy sources and environmental decontamination techniques. It is of fundamental interest to understand on a molecular level the aqueous solid/liquid interface, where photoca ...

Due to a significant influence of strontium (Sr) on bone regeneration, Sr substituted beta-tricalcium phosphate (Sr-TCP) cement is prepared and investigated by short- and long-term time-resolved techniques. For short-term investigations, energy-dispersive ...

The thesis covers the series of questions regarding the molecular structure and charge of oil nanodroplets in water. This work proposes a mechanism responsible for the stabilization of oil nanodroplets in water, which does not involve OH- adsorption. First ...

The surface of the Earth is snow-covered at least seasonally over large areas. This snow surface is highly dynamic, particularly under the influence of strong winds. The motion of snow particles driven by the wind not only changes the snow cover but has im ...

We consider fundamental algorithmic number theoretic problems and their relation to a class of block structured Integer Linear Programs (ILPs) called 2-stage stochastic. A 2-stage stochastic ILP is an integer program of the form min{c(T)x vertical bar Ax = ...

Pearl's do calculus is a complete axiomatic approach to learn the identifiable causal effects from observational data. When such an effect is not identifiable, it is necessary to perform a collection of often costly interventions in the system to learn the ...

Ru/CNF catalysts of different Ru nanoparticle (NP) sizes (0.9-2.7 nm) were assessed for their performance in continuous supercritical water gasification (SCWG) of glycerol. A structure sensitivity of Ru was demonstrated, with high initial turnover frequenc ...

Cancer is one of the leading causes of death globally. Immunotherapy represents one of the most promising cancer treatments inducing complete and durable responses in a fraction of cancer patients. Despite the unprecedented clinical success achieved by T c ...

We investigate the presence of a surface species for the active pharmaceutical ingredient (API) AZD9496 with dynamic nuclear polarization surface enhanced nuclear spectroscopy (DNP SENS). We show that using DNP we can elucidate the presence of an amorphous ...

Recent advancement in quantitative liquid-jet photoelectron spectroscopy enables the accurate determination of the absolute-scale electronic energetics of liquids and species in solution. The major objective of the present work is the determination of the ...

Nowadays, drug encapsulation and drug release from cellulose nanofibrils systems are intense research topics, and commercial grades of cellulose nanomaterials are currently available. In this work we present an ester-containing prodrug of metronidazole tha ...

We show that Cutting Planes (CP) proofs are hard to find: Given an unsatisfiable formula F, It is -hard to find a CP refutation of F in time polynomial in the length of the shortest such refutation; and unless Gap-Hitting-Set admits a nontrivial algorithm, ...

Water is ubiquitous on Earth, playing a critical role for a plethora of structures, processes and chemical reactions in nature. Its unique physicochemical properties originate mainly from its hydrogen bond network. Despite its recognized importance, many a ...

Multiple myeloma is a prevalent and incurable disease, despite the development of new and effective drugs. The recent development of chimeric antigen receptor (CAR)T cells has shown impressive results in the treatment of patients with relapsed or refractor ...

Glenohumeral osteoarthritis is a degenerative shoulder joint disease, which causes the breakdown of articular cartilage and bone. People affected by this disease suffer from severe pain and eventually reduced mobility and poor life quality. This disease is ...

We study the computations that Bayesian agents undertake when exchanging opinions over a network. The agents act repeatedly on their private information and take myopic actions that maximize their expected utility according to a fully rational posterior be ...

Knowledge of the oxidation state of metal centres in compounds and materials helps in the understanding of their chemical bonding and properties. Chemists have developed theories to predict oxidation states based on electron-counting rules, but these can f ...

Catechol Containing Polyelectrolyte Complex Nanoparticles as Local Drug Delivery System for Bortezomib at Bone Substitute Materials

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Second harmonic scattering of nanoparticles: A journey into the electrical double layer

Extractable Witness Encryption for the Homogeneous Linear Equations Problem

Nanoscale modelling of ionic transport in the porous C-S-H network

Molecular insights into the electrical double layer of colloidal oxide particles obtained through second harmonic scattering

Strontium Substituted Tricalcium Phosphate Bone Cement: Short and Long-Term Time-Resolved Studies and In Vitro Properties

Resolving the charging paradox of neat oil droplets in water

Modeling Snow Saltation: The Effect of Grain Size and Interparticle Cohesion

The double exponential runtime is tight for 2-stage stochastic ILPs

Minimum Cost Intervention Design for Causal Effect Identification

Particle Size Effects in Ru/CNF Catalysts during Supercritical Water Gasification of Glycerol

Mechanical Immunoengineering of T Cells for Enhanced Cancer Immunotherapy

High Sensitivity Detection of a Solubility Limiting Surface Transformation of Drug Particles by DNP SENS

Quantitative electronic structure and work-function changes of liquid water induced by solute

Two-step immobilization of metronidazole prodrug on TEMPO cellulose nanofibrils through thiol-yne click chemistry for in situ controlled release

Automating cutting planes is NP-hard

Molecular ordering effects in bulk and at lipid/water nanoscopic interfaces: A story of water, light, and order

Preclinical development of a humanized chimeric antigen receptor against B-cell maturation antigen for multiple myeloma

Overcorrected Implants for Total Shoulder Arthroplasty

Bayesian Decision Making in Groups is Hard

Using collective knowledge to assign oxidation states of metal cations in metal-organic frameworks