Selective Integrin alpha(5)beta(1) Targeting through Spatially Constrained Multivalent DNA-Based Nanoparticles

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We couple free electrons to the optical modes of a photonic microring resonator. Inelastic electron scattering leads to the generation of cavity photons, correlated to the electrons in time and energy loss. ...

Although the advent of organoids has opened unprecedented perspectives for basic and translational research, immune system-related organoids remain largely underdeveloped. Here, we established organoids from the thymus, the lymphoid organ responsible for T ...

Antimicrobial peptides (AMPs) are innate immune effectors first studied for their role in host defence. Recent studies have implicated these peptides in the clearance of aberrant cells and in neurodegenerative syndromes. In Drosophila, many AMPs are produc ...

The last decade has seen the development of a wide set of tools, such as wavefront shaping, computational or fundamental methods, that allow us to understand and control light propagation in a complex medium, such as biological tissues or multimode fibers. ...

The hematopoietic stem cell niche constitutes a complex bone marrow (BM) microenvironment. Osteoporosis is characterized by both reduced bone mineral density (BMD) and microarchitectural deterioration, constituting the most frequent alteration of the BM mi ...

Mesenteric lymph nodes (mLNs) are sentinel sites of enteral immunosurveillance and immune homeostasis. Immune cells from the gastrointestinal tract (GIT) are constantly recruited to the mLNs in steady-state and under inflammatory conditions resulting in th ...

Hepatocytes compose up to 80% of the total liver and have been indicated as important players in the induction of immunologic tolerance in this organ. We show that hepatocytes possess the molecular machinery required for the cross-presentation of extracell ...

Dendritic cells (DCs) are professional antigen-presenting cells involved in the initiation of immune responses. We generated a tolerogenic DC (tolDC) line that constitutively secretes interleukin-10 (IL10-DCs), expressed lower levels of co-stimulatory and ...

Eigenmodes are central to the study of resonant phenomena in all areas of physics. However, their use in nano-optics seems to have been hindered and delayed for various reasons. First, due to their small size, the response of nanostructures to a far-field ...

The effects of 107 MeV Kr-84(17+) ion irradiation on YBa2Cu3O7-x-based second-generation coated conductors were investigated using a combination of transmission electron microscopy, diffraction and X-ray energy dispersive spectrometry. Defects 3-5 nm in di ...

Selective Integrin alpha(5)beta(1) Targeting through Spatially Constrained Multivalent DNA-Based Nanoparticles

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Coupling Free Electrons and Cavity Photons in a Transmission Electron Microscope

Thymic epithelial organoids mediate T-cell development

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Learning the rules of mitochondrial network dynamics using generative models

Roadmap on wavefront shaping and deep imaging in complex media

Differential Blood Counts Do Not Consistently Predict Clinical Measurements of Bone Mineral Density and Microarchitecture at Homeostasis

Mesenteric Lymph Node Transplantation in Mice to Study Immune Responses of the Gastrointestinal Tract

Soluble N-Acetylgalactosamine-Modified Antigens Enhance Hepatocyte-Dependent Antigen Cross-Presentation and Result in Antigen-Specific CD8(+) T Cell Tolerance Development

IL10-and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression

Eigenmode Analysis in Plasmonics: Application to Second Harmonic Generation and Electron Energy Loss Spectroscopy

Structure analysis of the YBCO layer in Ag/YBCO/metal oxide buffer/Hastelloy composite tape before and after 107 MeV Kr17+ irradiation