Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

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Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells to form intracellular bacterial communities (IBCs) during early stages of urinary tract infections. However, the dynamic responses of IBCs to host stresses and anti ...

The metabolic capabilities of the species and the local environment shape the microbial interactions in a community either through the exchange of metabolic products or the competition for the resources. Cells are often arranged in close proximity to each ...

Urinary tract infections (UTIs) are amongst the most common bacterial infections and are the second-most frequent reason for antibiotic prescriptions. Moreover, in about 25% of all treated cases, recurrence of infection occurs. Uropathogenic Escherichia co ...

To reveal rare phenotypes in bacterial populations, conventional microbiology tools should be advanced to generate rapid, quantitative, accurate, and high-throughput data. The main drawbacks of widely used traditional methods for antibiotic studies include ...

Cellular respiration is a fundamental feature of metabolic activity and oxygen consumption can be considered as a reliable indicator of bacterial aerobic respiration, including for facultative anaerobic bacteria like E. coli. Addressing the emerging global ...

We report an oxidative ring-opening strategy to transform acyl, sulfonyl or carbamate protected aminocyclopropanes into 1,3-dielectrophilic carbon intermediates bearing a halide atom (Br, I) and a N,O-acetal. Replacing the alkoxy group of the N,O-acetal ca ...

In the present work, we study the fabrication of self-cleaning antibacterial surfaces, active under indoor or outdoor light. In order to obtain the highest activity with the lowest complexity we assess mild conditions of preparation (temperatures), pre-tre ...

Design and Synthesis of 16-Membered Cyclopeptides Active Against Vancomycin-resistant Enterococci (VRE)

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Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

Spatio-temporal modeling of the crowding conditions and metabolic variability in microbial communities

Microtissue models for studying the dynamics of host-pathogen interactions in the urinary bladder

Revealing Antibiotic Tolerance of the Mycobacterium smegmatis Xanthine/Uracil Permease Mutant Using Microfluidics and Single-Cell Analysis

Antimicrobial susceptibility testing by measuring bacterial oxygen consumption on an integrated platform

1,3-Difunctionalization of Aminocyclopropanes via Dielectrophilic Intermediates

Iron-coated polymer films with high antibacterial activity under indoor and outdoor light, prepared by different facile pre-treatment and deposition methods