Intraneural stimulation elicits discrimination of textural features by artificial fingertip in intact and amputee humans

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Timing is Everything

Karen Adam

In this thesis, timing is everything. In the first part, we mean this literally, as we tackle systems that encode information using timing alone. In the second part, we adopt the standard, metaphoric interpretation of this saying and show the importance of ...

EPFL2022

A Time Encoding Approach to Training Spiking Neural Networks

Karen Adam

While Spiking Neural Networks (SNNs) have been gaining in popularity, it seems that the algorithms used to train them are not powerful enough to solve the same tasks as those tackled by classical Artificial Neural Networks (ANNs).In this paper, we provide ...

IEEE2022

Improved spiking neural network for intershaft bearing fault diagnosis

Jun Wang

The intershaft bearing is located between the high and low-pressure rotors of the aero-engine, where the working environment is harsh, the load variation range is large, and the lubrication and heat dissipation are poor. The fault of the intershaft bearing ...

ELSEVIER SCI LTD2022

Breathing is coupled with voluntary initiation of mental imagery

Olaf Blanke, Oliver Alan Kannape, Hyeongdong Park

Previous research has suggested that bodily signals from internal organs are associated with diverse cortical and subcortical processes involved in sensory-motor functions, beyond homeostatic reflexes. For instance, a recent study demonstrated that the pre ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

Kernel Memory Networks: A Unifying Framework for Memory Modeling

Wulfram Gerstner, Johanni Michael Brea, Georgios Iatropoulos

We consider the problem of training a neural network to store a set of patterns with maximal noise robustness. A solution, in terms of optimal weights and state update rules, is derived by training each individual neuron to perform either kernel classifica ...

Curran Associates2022

Topology of synaptic connectivity constrains neuronal stimulus representation, predicting two complementary coding strategies

Michael Reimann, Ran Levi, Christoph Pokorny

In motor-related brain regions, movement intention has been successfully decoded from invivo spike train by isolating a lower-dimension manifold that the high-dimensional spiking activity is constrained to. The mechanism enforcing this constraint remains u ...

PUBLIC LIBRARY SCIENCE2022

Methods for acute and long-term imaging of the ventral nerve cord in behaving adult Drosophila

Laura Joan Hermans

Understanding how neural circuits remodel and adapt to animal behavior is a central theme in the field of Neuroscience. One strategy to reach this goal is to repeatedly record the same animal's neural circuits and observe how they adapt when facing differe ...

EPFL2022

A modeling framework to understand and optimize ultrasound neuromodulation

Théo Lemaire

Over the last decade, Low Intensity Focused Ultrasound Stimulation (LIFUS) has emerged as an attractive technology to modulate the activity of deep neural targets without invasive procedures. However, the underlying mechanisms by which ultrasonic waves can ...

EPFL2021

Computational model of the dorsal horn circuitry for innocuous touch

Silvestro Micera, Simone Romeni

Providing a naturalistic tactile sensory feedback is currently one of the key challenges in neuroprosthetics. Modeling has played a fundamental role in the development of "biomimetic" stimulation protocols, determining optimal activation patterns to be eli ...

IEEE2021

Evidence accumulation relates to perceptual consciousness and monitoring

Wenwen Chang, Olaf Blanke, Fosco Bernasconi, Nathan Quentin Faivre, Michael Eric Anthony Pereira

A fundamental scientific question concerns the neural basis of perceptual consciousness and perceptual monitoring resulting from the processing of sensory events. Although recent studies identified neurons reflecting stimulus visibility, their functional r ...

Nature Research2021

Computational approaches to decode grasping force and velocity level in upper-limb amputee from intraneural peripheral signals

Silvestro Micera, Ivo Strauss, Giacomo Valle

Objective. Recent results have shown the potentials of neural interfaces to provide sensory feedback to subjects with limb amputation increasing prosthesis usability. However, their advantages for decoding motor control signals over current methods based o ...

IOP Publishing Ltd2021

MorphoSONIC: A morphologically structured intramembrane cavitation model reveals fiber-specific neuromodulation by ultrasound

Elena Vicari, Silvestro Micera, Esra Neufeld, Théo Lemaire

Low-Intensity Focused Ultrasound Stimulation (LIFUS) holds promise for the remote modulation of neural activity, but an incomplete mechanistic characterization hinders its clinical maturation. Here we developed a computational framework to model intramembr ...

CELL PRESS2021