A time-gated large-array SPAD camera for picosecond resolution real-time FLIM

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PHz Electronic Device Design and Simulation for Waveguide-Integrated Carrier-Envelope Phase Detection

Yujia Yang

Carrier-envelope phase (CEP) detection of ultrashort optical pulses and low-energy waveform field sampling have recently been demonstrated using direct time-domain methods that exploit optical-field photoemission from plasmonic nanoantennas. These devices ...

IEEE Institute of Electrical and Electronics Engineers2022

Method and light microscope with a plurality of arrays of photon-counting detector elements

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic

A method for operating a light microscope comprises emitting and guiding a plurality of illumination light beams towards a specimen (6) to form a plurality of separated illumination light spots (2A, 2B, 2C, 2D) at the specimen; and guiding detection light ...

2022

Plasmon-induced near-infrared fluorescence enhancement of single-walled carbon nanotubes

Giulia Tagliabue, Ardemis Anoush Boghossian, Shang-Jung Wu, Alessandra Antonucci, Theodoros Tsoulos, Amirmostafa Amirjani, Sayyed Hashem Sajjadi

Single-walled carbon nanotubes (SWCNTs) emit near-infrared (NIR) fluorescence that is ideal for optical sensing. However, the low quantum yields diminish the sensor’s signal-to-noise ratio and limits the penetration depths for in vivo measurements. In this ...

2022

Status of the K-EUSO Orbital Detector of Ultra-High Energy Cosmic Rays

Andrii Neronov

K-EUSO (KLYPVE-EUSO) is a planned orbital mission aimed at studying ultra-high energy cosmic rays (UHECRs) by detecting fluorescence and Cherenkov light emitted by extensive air showers in the nocturnal atmosphere of Earth in the ultraviolet (UV) range. Th ...

MDPI2022

NIR Fluorescence lifetime macroscopic imaging with a time-gated SPAD camera

Edoardo Charbon, Claudio Bruschini, Arin Can Ülkü

The performance of SwissSPAD2 (SS2), a large scale, widefield time-gated CMOS SPAD imager developed for fluorescence lifetime imaging, has recently been described in the context of visible range and fluorescence lifetime imaging microscopy (FLIM) of dyes w ...

SPIE-INT SOC OPTICAL ENGINEERING2022

Impulsive noise removal via a blind CNN enhanced by an iterative post-processing

Hatef Otroshi Shahreza, Seyedeh Sahar Sadrizadeh

In digital imaging, especially in the process of data acquisition and transmission, images are often affected by impulsive noise. Therefore, it is essential to remove impulsive noise from images before any further processing. Due to the remarkable performa ...

ELSEVIER2022

Large-Format Time-Gated SPAD Cameras for Real-Time Phasor-Based FLIM

Arin Can Ülkü

Fluorescence lifetime imaging microscopy (FLIM) is an imaging modality often used to monitor biochemical properties of a cell or a tissue. In addition to conventional fluorescence microscopy features, such as selective labeling and non-invasiveness, FLIM e ...

EPFL2021

A Pixel Design of a Branching Ultra-Highspeed Image Sensor

Edoardo Charbon

A burst image sensor named Hanabi, meaning fireworks in Japanese, includes a branching CCD and multiple CMOS readout circuits. The sensor is backside-illuminated with a light/charge guide pipe to minimize the temporal resolution by suppressing the horizont ...

2021

Direct time-of-flight SPAD image sensors for light detection and ranging

Preethi Padmanabhan

Depth sensing is an increasingly important feature in many applications of consumer, automotive, augmented/virtual reality (AR-VR), space and bio-medical imaging. Long range, high depth resolution, high spatial resolution, and high frame rates are often co ...

EPFL2021

Low-power image sensor system with single-photon avalanche diode photodetectors

Edoardo Charbon, Claudio Bruschini, Ivan Michel Antolovic

The invention relates to an image sensor comprising a photodetector array including neighboring photodetector elements, each photodetector element comprising: - a photodetector cell having a photodiode and a reset unit; - a cell control unit coupled with t ...

2021

Megapixel SPAD cameras for time-resolved applications

Kazuhiro Morimoto

Progress in optics technology has enriched our daily lives in many ways. Various types of single-photon detector technologies have emerged in the last century. Among these, single-photon avalanche diode (SPAD) technology outperforms other detectors for its ...

EPFL2020