Nongenetic Evolution Drives Lung Adenocarcinoma Spatial Heterogeneity and Progression

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Survival outcomes of primary vs interval cytoreductive surgery for International Federation of Gynecology and Obstetrics stage IV ovarian cancer: a nationwide population-based target trial emulation

Elise Hélène Dumas

BACKGROUND: The effect of primary cytoreductive surgery vs interval cytoreductive surgery on International Federation of Gynecology and Obstetrics stage IV ovarian cancer outcomes remains uncertain and may vary depending on the stage and the location of ex ...

MOSBY-ELSEVIER2025

A diffusion MRI model for random walks confined on cylindrical surfaces: towards non-invasive quantification of myelin sheath radius

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Elda Fischi Gomez

Introduction Quantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders. Despite advancements in diffusion MRI (dMRI) microstructure techniques, there are curre ...

FRONTIERS MEDIA SA2025

Self-rule to multi-adapt: Generalized multi-source feature learning using unsupervised domain adaptation for colorectal cancer tissue detection

Jean-Philippe Thiran, Seyedbehzad Bozorgtabar, Christian Robert Abbet

Supervised learning is constrained by the availability of labeled data, which are especially expensive to acquire in the field of digital pathology. Making use of open-source data for pre-training or using domain adaptation can be a way to overcome this is ...

ELSEVIER2022

GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer

Bart Deplancke, Etienne Meylan, Petra Catalina Schwalie, Svenja Johanna Groeneveld, Jessica Christine Vazquez, Natasha Ella Samson, Mark Jonathan Masin

Alterations in glucose metabolism and epithelial-mesenchymal transition (EMT) constitute two important characteristics of carcinoma progression toward invasive cancer. Despite an extensive characterization of each of them separately, the links between EMT ...

2014