Reducing OLTP Instruction Misses With Thread Migration

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Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study

Jacques Fellay, Christian Axel Wandall Thorball

Leukocyte count is associated with coronary artery disease (CAD) events in the general population. Here we show that leukocytes are independently associated with CAD events in people with HIV in Switzerland, after adjusting for traditional and HIVrelated r ...

OXFORD UNIV PRESS INC2023

Rebooting Virtual Memory with Midgard

Siddharth Gupta

Virtual Memory (VM) is a critical programming abstraction that is widely used in various modern computing platforms. With the rise of datacenter computing and birth of planet-scale online services, the semantic and capacity requirements from memory have ev ...

EPFL2023

Atomic-level structure determination of amorphous molecular solids by NMR

David Lyndon Emsley, Arthur César Pinon, Manuel Cordova, Pinelopi Moutzouri

Structure determination of amorphous materials remains challenging, owing to the disorder inherent to these materials. Nuclear magnetic resonance (NMR) powder crystallography is a powerful method to determine the structure of molecular solids, but disorder ...

Nature Portfolio2023

Building Chips Faster: Hardware-Compiler Co-Design for Accelerated RTL Simulation

Sahand Kashani

The demise of Moore's Law and Dennard scaling has resulted in diminishing performance gains for general-purpose processors, and so has prompted a surge in academic and commercial interest for hardware accelerators. Specialized hardware has already redefine ...

EPFL2023

HPCache: memory-efficient OLAP through proportional caching revisited

Anastasia Ailamaki, Periklis Chrysogelos, Hamish Mcniece Hill Nicholson

Analytical engines rely on in-memory data caching to avoid storage accesses and provide timely responses by keeping the most frequently accessed data in memory. Purely frequency- and time-based caching decisions, however, are a proxy of the expected query ...

Springer2023

SecureCells: A Secure Compartmentalized Architecture

Andrés Sánchez Marín, Babak Falsafi, Mathias Josef Payer, Siddharth Gupta, Atri Bhattacharyya, Yuanlong Li, Florian Hofhammer

Modern programs are monolithic, combining code of varied provenance without isolation, all the while running on network-connected devices. A vulnerability in any component may compromise code and data of all other components. Compartmentalization separates ...

2023

uKharon: A Membership Service for Microsecond Applications

Rachid Guerraoui, Javier Picorel Obando, Athanasios Xygkis, Antoine Murat

Modern data center fabrics open the possibility of microsecond distributed applications, such as data stores and message queues. A challenging aspect of their development is to ensure that, besides being fast in the common case, these applications react fa ...

USENIX Association2023

Chaosity: Understanding Contemporary NUMA-architectures

Andreea Nica, Anastasia Ailamaki, Viktor Sanca, Syed Mohammad Aunn Raza, Hamish Mcniece Hill Nicholson

Modern hardware is increasingly complex, requiring increasing effort to understand in order to carefully engineer systems for optimal performance and effective utilization. Moreover, established design principles and assumptions are not portable to modern ...

2023

2D Nanosystems: Applications of 2D Semiconductors for In-Memory Computing

Guilherme Migliato Marega

Machine learning and data processing algorithms have been thriving in finding ways of processing and classifying information by exploiting the hidden trends of large datasets. Although these emerging computational methods have become successful in today's ...

EPFL2023