Publication

Effect of Lower Limb vs. Abdominal Compression on Mobility in Orthostatic Hypotension: A Single-Blinded, Randomized, Controlled, Cross-Over Pilot Study in Parkinson's Disease

Publications associées (19)

Implanted System for Orthostatic Hypotension in Multiple-System Atrophy

Léonie Asboth, Maxime Berney, Grégoire Courtine, Nicolas Hankov, Robin Jonathan Demesmaeker, Jocelyne Bloch, Sergio Daniel Hernandez, Jordan Squair, Grégory Didier Dumont, Suje Amir

Orthostatic hypotension is a cardinal feature of multiple-system atrophy. The upright posture provokes syncopal episodes that prevent patients from standing and walking for more than brief periods. We implanted a system to restore regulation of blood press ...

MASSACHUSETTS MEDICAL SOC2022

Electrical spinal cord stimulation protocols to regulate motor and autonomic functions in people with neurological disorders

Robin Jonathan Demesmaeker

Neurological disorders such as spinal cord injury (SCI) massively reduce independence and quality of life. Most often, the majority of the nervous system is still fully or partially spared, but dysfunctional due to aberrant or absent descending input from ...

EPFL2021

Designing Gamified Activities with Haptic-Enabled Tangible Robots for Therapy and Assistance

Arzu Güneysu Özgür

In this thesis, we contribute to the field of rehabilitation robotics by designing haptic-enabled tangible robot-based activities and exploring their added value for therapy and assistance. The research specifically focuses on the design and development of ...

EPFL2021

Electrical spinal cord stimulation protocols to regulate neurological functions after spinal cord injury

Salif Axel Komi

Spinal cord injury (SCI) is a life-changing event. People who suffer from it lose their ability to move normally and are subject to life-threatening symptoms. When the insult is not too severe, partial recovery is possible. Otherwise, for severely affected ...

EPFL2021

Clinical value of assessing motor performance in postacute stroke patients

Kamiar Aminian, Anisoara Ionescu, Fabien Massé

Background Rehabilitative treatment plans after stroke are based on clinical examinations of functional capacity and patient-reported outcomes. Objective information about daily life performance is usually not available, but it may improve therapy personal ...

BioMed Central2021

Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease

Hilal Lashuel, Magdalena Zweckstetter

With the advent of the genetic era in Parkinson's disease (PD) research in 1997, alpha-synuclein was identified as an important player in a complex neurodegenerative disease that affects >10 million people worldwide. PD has been estimated to have an econom ...

NATURE RESEARCH2021

Iterative Design and Evaluation of a Tangible Robot-Assisted Handwriting Activity for Special Education

Pierre Dillenbourg, Thibault Lucien Christian Asselborn, Ayberk Özgür, Arzu Güneysu Özgür, Wafa Monia Benkaouar Johal, Elmira Yadollahi, Barbara Bruno

In this article we investigate the role of interactive haptic-enabled tangible robots in supporting the learning of cursive letter writing for children with attention and visuomotor coordination issues. We focus on the two principal aspects of handwriting ...

2020

A method for fast automated assessment of the magnetic resonance parkinsonism index

Bénédicte Marie Maréchal

In patients with parkinsonian syndromes, and particularly during the early stages of the clinical disease, differentiating between idiopathic Parkinson's disease and progressive supranuclear palsy is challenging. Imaging plays an important role in early di ...

SPRINGER2020

Locomotion and cadence detection using a single trunk-fixed accelerometer: validity for children with cerebral palsy in daily life-like conditions

Kamiar Aminian, Anisoara Ionescu, Lena Carcreff, Stéphane Armand

BACKGROUND: Physical therapy interventions for ambulatory youth with cerebral palsy (CP) often focus on activity-based strategies to promote functional mobility and participation in physical activity. The use of activity monitors validated for this populat ...

BioMed Central2019

The Adapted Lifestyle-Integrated Functional Exercise Program for Preventing Functional Decline in Young Seniors: Development and Initial Evaluation

Wei Zhang

Background: The Lifestyle-integrated Functional Exercise (LiFE) program is an intervention integrating balance and strength activities into daily life, effective at reducing falls in at-risk people >= 70 years. There is potential for LiFE to be adapted to ...

KARGER2019

Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study

Nikolaos Stergiopoulos, Nico Westerhof, Elira Maksuti

During aging, systolic blood pressure continuously increases over time, whereas diastolic pressure first increases and then slightly decreases after middle age. These pressure changes are usually explained by changes of the arterial system alone (increase ...

Public Library of Science2016

Physical activity monitoring based on wearable technology combining inertial and barometric pressure sensors : application to stroke patients

Fabien Massé

Stroke, or cerebral-vascular accident is the leading cause of disabilities in the western world. It primarily affects mobility due to a degradation of principal motor functions such as balance and gait. This reduction of mobility directly impacts the spect ...

EPFL2015

Facial rehabilitative device based on robogami (robotic origami) platform

Jamie Paik, Amir Firouzeh

The present invention relates to a facial rehabilitative device based on Robogami (Robotic Origami) platform. The device facilitates the process of the physical therapy for the therapist, to make this process more disciplined, and to enhance the result for ...

2015

Exploring the pathological interaction between LRRK2 and alpha-synuclein : two key genes implicated in Parkinson's disease

Alessandra Musso

Parkinson’s disease (PD) is the most common age-related neurodegenerative movement disorder that affects 1-2% of the general population over the age of 65 and rising to 4-5% over 80 years of age. It is estimated that 6.3 million people worldwide have Parki ...

EPFL2014

Physical activity recognition via minimal in-shoes force sensor configuration

Kamiar Aminian, Arash Arami, Fabien Massé, Christopher Moufawad El Achkar

We propose a new minimal wearable system and a classifier for physical activity recognition. The configuration is solely based on two force sensors placed anteriorly and posteriorly under the feet. To find the optimal sensor configuration, we estimated the ...

IEEE2013

Physical activity recognition via minimal in-shoes force sensor configuration

Kamiar Aminian, Arash Arami, Fabien Massé, Christopher Moufawad El Achkar

Ieee2013

Neurodegenerative phenotypes in an A53T-synuclein transgenic mouse model are independent of LRRK2

Darren Moore, Alessandra Musso

Mutations in the genes encoding LRRK2 and -synuclein cause autosomal dominant forms of familial Parkinsons disease (PD). Fibrillar forms of -synuclein are a major component of Lewy bodies, the intracytoplasmic proteinaceous inclusions that are a pathologic ...

Oxford University Press2012

Ambulatory monitoring of motor functions in patients with Parkinson's disease using kinematic sensors

Arash Salarian

Parkinson's disease (PD) is the second most common neurodegenerative disease in the general population. Cardinal symptoms of Parkinson's disease are resting tremor, rigidity, akinesia and bradykinesia and in advanced stages, gait impairments, postural inst ...

EPFL2006

A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension

Patrick Aebischer, Nicole Déglon

Current therapy for several forms of anemia involves a weekly regime of multiple subcutaneous injections of recombinant human erythropoietin (hEpo). In an effort to provide a physiologically regulated administration of erythropoietin, we are developing cel ...

1997