Publication

Mechanism of ultrafast non-reactive deactivation of the retinal chromophore in non-polar solvents

Publications associées (7)

Long-lived Photo-Charges in 1D Helical Organic Semiconductor Nanostructures

The formation of photoexcited states in organic semiconductors, their separation into long-lived or stable charge carriers, as well as the charge transport are critical processes relevant to several important research fields and emerging technologies. Whil ...

EPFL2018

How Rhodopsin Tunes the Equilibrium between Protonated and Deprotonated Forms of the Retinal Chromophore

Ursula Röthlisberger, Alicia Solano, Siri Camee van Keulen

Rhodopsin is a photoactive G-protein-coupled receptor (GPCR) that converts dim light into a signal for the brain, leading to eyesight. Full activation of this GPCR is achieved after passing through several steps of the protein's photoactivation pathway. Ke ...

2017

Generalized QM/MM Force Matching Approach Applied to the 11-cis Protonated Schiff Base Chromophore of Rhodopsin

Ursula Röthlisberger, Ivano Tavernelli, Pablo Campomanes Ramos, Manuel Dömer

We extended a previously developed force matching approach to systems with covalent QM/MM boundaries and describe its user-friendly implementation in the publicly available software package CPMD. We applied this approach to the challenging case of the reti ...

2014

An artificial molecular switch that mimics the visual pigment and completes its photocycle in picoseconds

Stefan Haacke, Majed Chergui, Andrea Cannizzo

Single mols. that act as light-energy transducers (e.g., converting the energy of a photon into at.-level mech. motion) are examples of minimal mol. devices. Here, we focus on a mol. switch designed by merging a conformationally locked diarylidene skeleton ...

National Academy of Sciences2008

Vibrational coherences of the protonated Schiff base of all-trans-retinal in solution

Stefan Haacke, Majed Chergui, Goran Zgrablic

Modulations in the time gated ultrafast fluorescence of the protonated Schiff base of retinal in various solvents are reported, which reflect the creation and evolution of vibrational wave packets due to the torsional mode of retinal of frequency .apprx.12 ...

2007

Solvent effects on the ultrafast dynamics of the retinal chromophore of bacteriorhodopsin

Goran Zgrablic

Photo-induced excited-state reactions stand in the center of function of the photosensitive biological systems. These reactions can be accompanied by structural changes of the chromophore (for example isomerization) which are influenced by the nearest envi ...

EPFL2006

Solvent and protein effects on the structure and dynamics of the rhodopsin chromophore

Ursula Röthlisberger, Leonardo Guidoni

The structure and dynamics of the retinal chromophore of rhodopsin are investigated systematically in different environments (vacuum, methanol soln., and protein binding pocket) and with different computational approaches (classical, quantum, and hybrid qu ...

2005