Publications associées à Multiscale Porosity Microfluidics to Study Bacterial Transport in Heterogeneous Chemical Landscapes

Publications associées (38)

Additive Manufacturing of Stretchable Zipping Electrostatic Actuators through Spray Encapsulation of a Frozen Liquid

The fabrication of soft fluid-filled systems with mm or sub-mm scale features such as tuneable lenses, microfluidic tactile sensors, and electrohydraulic zipping actuators often relies on manual filling. This final step of injecting fluid limits throughput ...

Wiley2025

Fluid-network relations: Decay laws meet with spatial self-similarity, scale invariance, and control scaling

Yizhou Xu

Diverse implicit structures of fluids have been discovered recently, providing opportunities to study the physics of fluids applying network analysis. Although considerable work has been devoted to identifying the informative network structures of fluids, ...

2024

Improved microfluidic transcriptome based screening methods

Christoph Merten, Leonie Kolmar, Xiaoli Ma, Hongxing Hu

The invention provides microfluidic screening systems for the identification of compounds or compositions influencing cellular transcriptomes. The invention is predicated upon taking into account differences in newly synthesized mRNA in contrast to so call ...

2024

Water weakening and the compressive brittle strength of carbonates: Influence of fracture toughness and static friction

Marie Estelle Solange Violay, Corentin Jean-Marie Rémi Noël, Barnaby Padraig Fryer

Water is ubiquitous within the pore space of rocks and has been shown to affect their physical and mechanical behaviour. Indeed, water can act on the rock strength via mechanical (i.e., reducing the effective stresses) or chemical effects (e.g., mineral di ...

2024

Influence of pore-scale heterogeneity on the precipitation patterns in Microbially Induced Calcite Precipitation (MICP)

Ariadni Elmaloglou

The principle of tailoring material properties to improve the mechanical behaviour of soils through compaction or cement grouting dates to the 60s. The increasing trends of urbanization worldwide require new solutions for the development of resilient and s ...

EPFL2023

Modified capillary number to standardize droplet generation in suction-driven microfluidics

Jatin Panwar

In droplet microfluidic devices with suction-based flow control, the microchannel geometry and suction pressure at the outlet govern the dynamic properties of the two phases that influence the droplet generation. Therefore, it is critical to understand the ...

Springer Heidelberg2024

Microfluidic devices

Matthias Lütolf, Jisoo Park

The present disclosure relates to a microfluidic device comprising: a substrate; a culture chamber (130); a loading channel (170) in fluid communication with the culture chamber; at least one auxiliar channel (170-1, 5 170-2) extending from and in fluid co ...

2023

Microfluidic systems for infectious disease diagnostics

Martinus Adela Maria Gijs, Thomas Lehnert

Microorganisms, encompassing both uni- and multicellular entities, exhibit remarkable diversity as omnipresent life forms in nature. They play a pivotal role by supplying essential components for sustaining biological processes across diverse ecosystems, i ...

Royal Soc Chemistry2024

Efficient AC electrothermal flow (ACET) on-chip for enhanced immunoassays

Martinus Adela Maria Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

Biochemical reaction rates in microfluidic systems are known to be limited by the diffusional transport of reagents, leading often to lowered sensitivity and/or longer detection times in immunoassays. Several methods, including electrically powering electr ...

ROYAL SOC CHEMISTRY2023

Nanoplasmonic Single-Tumoroid Microarray for Real-Time Secretion Analysis

Hatice Altug, Nicolas Antoine Vincent Broguiere, Yen-Cheng Liu, Luis Francisco Lorenzo Martin, Saeid Ansaryan, Jiayi Tan

Organoid tumor models have emerged as a powerful tool in the fields of biology and medicine as such 3D structures grown from tumor cells recapitulate better tumor characteristics, making these tumoroids unique for personalized cancer research. Assessment o ...

2024

Bacterial colonization in realistic environments: how mechanics impact biofilm formation in the wild and during infection

Tamara Rossy

A variety of physical inputs acts onto bacteria in nature. However, these are most often ignored in the studies of their physiology. There is now increasing evidence indicating that bacteria respond to physical stimuli, including mechanical forces. Yet, qu ...

EPFL2023

Impact of CO2-rich seawater injection on the flow properties of basalts

Cesare Griner, Lyesse Laloui, Eleni Stavropoulou

Permanent CO storage in basalts through mineralisation offers a promising solution for reducing carbon emissions and mitigating climate change. This study focuses on the impact of potential mineralisation on the flow properties of the basaltic material. Fl ...

2024

Crystal, defect, and morphology engineering of porous two-dimensional materials for ionic separation

Heng-Yu Chi

Ordered two-dimensional (2D) materials hosting Å-scale pores are highly promising for enabling challenging separation, thanks to well-defined pore geometry resulting in tight confinement of ions when hosted inside the pore. In addition, the 2D nature of th ...

EPFL2024

Acoustofluidic large-scale mixing for enhanced microfluidic immunostaining for tissue diagnostics

Martinus Adela Maria Gijs, Diego Gabriel Dupouy, Muaz Salama Abdelmonem Draz

The usage of microfluidics for automated and fast immunoassays has gained a lot of interest in the last decades. This integration comes with certain challenges, like the reconciliation of laminar flow patterns of micro-scale systems with diffusion-limited ...

ROYAL SOC CHEMISTRY2023

Electronic readout of DNA amplification in nanoliter chambers. Strategies towards highly parallel semiconductor-based nucleic acid amplification testing

Saurabh Tomar

Polymerase chain reaction (PCR) has been the most significant driver in the field of nucleic acid testing (NAT) since its invention. Popularized as an abbreviation by the Covid-19 pandemic, PCR-based methods are the gold standard in the field of diagnostic ...

EPFL2023

Surface functionalization strategies for optimal DNA conjugation on sensing surfaces for virus detection

Perrine Agnes Edith Robin

The COVID-19 pandemic has highlighted the need for new biodetection methods that would enable mass population screening, and help controlling the spread of viral diseases. Such technologies could benefit the prevention of many other infectious diseases. Fo ...

EPFL2024

Combination of dielectrophoretic and hydrodynamic traps for the controlled contact between cells or beads and application to adhesion assays

Clémentine Sophie Sarah Lipp

Multicellular organisms require very well organized and finely balanced cell-cell communication, adhesion and coordination to ensure the organisms homeostasis. These functions rely on specialized receptors placed at the cells membrane whose binding to thei ...

EPFL2023

Stability Threshold of the 2D Couette Flow in a Homogeneous Magnetic Field Using Symmetric Variables

Michele Dolce

We consider a 2D incompressible and electrically conducting fluid in the domain T x R. The aim is to quantify stability properties of the Couette flow (y, 0) with a constant homogenous magnetic field (beta, 0) when |beta|>1/2. The focus lies on the regime ...

Springer2024

Portable impedance-sensing device for microorganism characterization in the field

Sandro Carrara

A variety of biosensors have been proposed to quickly detect and measure the properties of individual microorganisms among heterogeneous populations, but challenges related to cost, portability, stability, sensitivity, and power consumption limit their app ...

Nature Portfolio2023

Dynamic Second Harmonic Imaging of Proton Translocation Through Water Needles in Lipid Membranes

Sylvie Roke, David Roesel, Seonwoo Lee

Proton translocation through lipid membranes is a fundamental process in the field of biology. Several theoretical models have been developed and presented over the years to explain the phenomenon, yet the exact mechanism is still not well understood. Here ...

American Chemical Society (ACS)2024