Publications associées à Computational approaches for spatialomics data: construction, integration and analysis of biomolecular atlases

Publications associées (11)

Fundamentals on the mechanisms involved in plasma-activated water decontamination

Plasma-activated water (PAW) is an innovative antimicrobial solution with great potential in enhancing food safety, advancing healthcare, and supporting environmental sustainability. This thesis investigates the inactivation mechanisms of \textit{Escherich ...

EPFL2025

Tracking Hyperpolarized [1-¹³C] Pyruvate and [1-¹³C] L-Lactate Metabolism in the Healthy and Post-Stroke Mouse Brain

Rolf Gruetter, Bernard Lanz, Mor-Miri Mishkovsky, Jean-Noël Hyacinthe, Thanh Phong Kevin Lê, Mario Gaetano Lepore, Lara Buscemi Estefanell, Elise Marie Catherine Vinckenbosch

Tracking hyperpolarized (HP) ¹³C labeling from either [1-¹³C] pyruvate or [1-¹³C] lactate is a useful tool to assess intermediary metabolism in vivo, which has already been translated from preclinical to clinical research. HP [1-¹³C] pyruvate and [1-¹³C] l ...

Wiley2025

Applications of semiclassical and mixed quantum-classical dynamics to study molecular systems with multiple electronic states

Alan Scheidegger

Computational simulations of quantum molecular dynamics are indispensable for understanding and predicting phenomena in physical chemistry. This thesis explores molecular processes where multiple electronic states play a role. A significant part of this wo ...

EPFL2025

Analyzing Various Biological Fluids with a Single Automated Proteomic Workflow for Biomarker Discovery

Loïc Dayon

The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.Protein biomarker discovery in human biological fluids has greatly developed over the past two decades thanks to technological advances allowing deeper ...

Springer US2025

Joint Multiband Deconvolution for Euclid and Vera C. Rubin Images

Frédéric Courbin, Pascale Jablonka, Utsav Akhaury

With the advent of surveys like Euclid and Vera C. Rubin, astrophysicists will have access to both deep, high-resolution images and multiband images. However, these two types are not simultaneously available in any single dataset. It is therefore vital to ...

EDP Sciences SA2025

Microscale droplet assembly enables biocompatible multifunctional modular iontronics

Yujia Zhang

Hydrogel iontronic devices can emulate biological functions and communicate with living matter. But the fabrication of miniature, soft iontronic devices according to modular designs has not been achieved. In this work, we report the use of surfactant-suppo ...

AMER ASSOC ADVANCEMENT SCIENCE2024

Impact of phylogeny on inference from protein sequences: from models to natural data

Nicola Dietler

Proteins are macromolecules considered as the building blocks of cells because they are at the heart of almost every cellular task, ranging from chemical to mechanical processes. For instance, proteins play a role as enzymes for digestion, transporters of ...

EPFL2024

Early intensive rehabilitation reverses locomotor disruption, decrease brain inflammation and induces neuroplasticity following experimental Cerebral Palsy

Grégoire Courtine, Yohan Van de Looij, Quentin Barraud, Laetitia Danielle Philippine Baud

Background: Cerebral Palsy (CP) is a major cause of motor and cognitive disability in children due to injury to the developing brain. Early intensive sensorimotor rehabilitation has been shown to change brain structure and reduce CP symptoms severity. We c ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2024

Unravelling the components of diffuse scattering using deep learning

Lucas Sebastian Powell-Rudden

Many technologically important material properties are underpinned by disorder and short-range structural correlations; therefore, elucidating structure-property relationships in functional materials requires understanding both the average and the local st ...

Int Union Crystallography2024

Unraveling behavioral individuality in Drosophila melanogaster: An automated high-throughput screening approach

Riddha Manna

Despite being genetically identical and reared under identical conditions, individual animals exhibit behavioural differences, which we call individuality. It remains unclear where these differences emerge in the causal cascade from transcription to gene p ...

EPFL2024

Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression

Stephan Morgenthaler

Background Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. CRC deaths can be reduced with prevention and early diagnosis. Circulating tumor DNA-based liquid biopsies, are emerging tools for cancer detection. However, ...

2024