Publications associées à Unravelling the Mesp1/2 Shared Regulatory Landscape - Insights into Developmental Gene Regulation by Using Gastruloids

Publications associées (6)

Dissecting the mechanisms of centriole stability in Caenorhabditis elegans: Focus on SAS-1

Centrioles are evolutionarily conserved microtubule-based organelles essential for cell division, ciliogenesis, and cell polarity. While centrioles are critical for many cellular processes, their selective elimination is crucial during specific development ...

EPFL2025

Evolution of Phenotypic Variance Provides Insights into the Genetic Basis of Adaptation

Ana Marija Jaksic

Most traits are polygenic, and the contributing loci can be identified by genome-wide association studies. The genetic basis of adaptation (adaptive architecture) is, however, difficult to characterize. Here, we propose to study the adaptive architecture o ...

Oxford Univ Press2024

Deciphering the role of signalling centers in limb development and regeneration

Jixing Zhong

Signaling centers are specialized groups of cells that release morphogens, guiding the fate and behavior of adjacent cells during morphogenesis. For instance, the apical-ectodermal-ridge (AER) in developing limbs, is crucial for coordinating cell fate and ...

EPFL2024

Transcriptomic and proteomic changes associated with cobalamin-dependent propionate production by the rumen bacterium Xylanibacter ruminicola

Ianina Altshuler

Xylanibacter ruminicola is an abundant rumen bacterium that produces propionate in a cobalamin (vitamin B12)-dependent manner via the succinate pathway. However, the extent to which this occurs across ruminal Xylanibacter and closely related bacteria, and ...

American Society for Microbiology2024

Extensive tissue-specific expression variation and novel regulators underlying circadian behavior

Matteo Dal Peraro, Bart Deplancke, Vincent Roland Julien Gardeux, Julie Marie Russeil, Alessio Prunotto, Maria Litovchenko, Michael Vincent Frochaux, Antonio Carlos Alves Meireles Filho, Brian Dennis Hollis, Roel Paulus Josephus Bevers, Virginie Sandra Braman

Natural genetic variation affects circadian rhythms across the evolutionary tree, but the underlying molecular mechanisms are poorly understood. We investigated population-level, molecular circadian clock variation by generating >700 tissue-specific transc ...

2021

Boosting the performance of inference algorithms for transcriptional regulatory networks using a phylogenetic approach

Bernard Moret, Xiuwei Zhang

Springer2008