Publication

Two-photon microscopy of the mouse cochlea in situ for cellular diagnosis

Publications associées (31)

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The coherent photogalvanic effect leads to the generation of a current under the absorption interference of coherent beams and allows for the inscription of space-charge gratings leading to a second-order susceptibility (chi((2))). The inscribed grating au ...

2022

Design and modelling of a compliant constant-force surgical tool for objective assessment of ossicular chain mobility

Simon Nessim Henein, Charles Baur, Loïc Benoît Tissot-Daguette

Surgeons generally assess the mobility of the ossicle chain by manual palpation using rigid elongated hooks inserted through the ear canal. As the applied forces are in the range of a few grams equivalent force, the measurement remains subjective and its r ...

IEEE2021

Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss

Nicolas Jean Philippe Guex

Non-Syndromic Hereditary Hearing Loss (NSHHL) is a genetically heterogeneous sensory disorder with about 120 genes already associated. Through exome sequencing (ES) and data aggregation, we identified a family with six affected individuals and one unrelate ...

Oxford University Press2021

Repeat stereotactic radiosurgery for progressive vestibular schwannomas after previous radiosurgery: a systematic review and meta-analysis

Constantin Tuleasca, Adrien Jean Régis Maurice Hilaire

Vestibular schwannomas (VS) are slow-growing intracranial extraaxial benign tumors, developing from the vestibular part of the eight cranial nerves. Stereotactic radiosurgery (SRS) has now a long-term scientific track record as first intention treatment fo ...

SPRINGER2021

A tunable femtosecond fiber laser source for multiphoton emission microscopy

Pierre-Marc Jean Marie Dansette

Second harmonic generation microscopy is used to image interfaces or non-centrosymmetric structures and molecules. Two-photon fluorescence microscopy can image molecules within cells without using markers. Thus those technics have lead to advances in our u ...

EPFL2021

Biodegradable Harmonophores for Targeted High-Resolution In Vivo Tumor Imaging

Sylvie Roke, Ali Yasin Sonay, Shahed Behzadi, Claire Jacqueline Léa Teulon, Sine Yaganoglu

Optical imaging probes have played a major role in detecting and monitoring a variety of diseases. In particular, nonlinear optical imaging probes, such as second harmonic generating (SHG) nanoprobes, hold great promise as clinical contrast agents, as they ...

2021

Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B

Bernard Schneider, Paola Andrea Solanes Vega

Viral delivery of exogenous coding sequences into the inner ear has the potential for therapeutic benefit for patients suffering genetic or acquired hearing loss. To devise improved strategies for viral delivery, we investigated two injection techniques, r ...

2020

Dissecting self-voice perception: From bone conduction to robotically-induced self-other voice misattribution in healthy listeners

Pavo Orepic

Inspired by the prominent theory suggesting that auditory-verbal hallucinations (AVH) - the sensation of hearing voices without present speakers - arise as misattribution of inner speech towards external agents, my thesis revolved around self-voice percept ...

EPFL2020

Modes interplay controls the second harmonic generation dynamics of plasmonic nanostructures

Olivier Martin, Gabriel David Bernasconi, Andrei Kiselev

A large amount of experimental and theoretical works deals with the second harmonic generation from different plasmonic geometries. Since they often consider relatively long optical pulses, many of these studies are focused on the investigation of a quasi- ...

SPIE2020

Peculiarities of second harmonic generation with chirped femtosecond pulses at high conversion efficiency

Pierre-Marc Jean Marie Dansette

Frequency doubling of an infrared laser radiation in non-linear optical crystals is a widely used technique to obtain light in the visible range. The second harmonic generation process is influenced by several well-known parameters. In this article we stud ...

ELSEVIER2020

Smaller, Faster & Lighter KNN Graph Constructions

Rachid Guerraoui, Anne-Marie Kermarrec, Olivier Ruas

We propose GoldFinger, a new compact and fast-to-compute binary representation of datasets to approximate Jaccard’s index. We illustrate the effectiveness of GoldFinger on the emblematic big data problem of K-Nearest-Neighbor (KNN) graph construction and s ...

2020