Publications associées à Modulating the DNA/Lipid Interface through Multivalent Hydrophobicity

Publications associées (9)

The intrinsically disordered regions of organellophagy receptors are interchangeable and control organelle fragmentation, ER-phagy and mitophagy flux

Organellophagy receptors control the generation and delivery of portions of their homing organelle to acidic degradative compartments to recycle nutrients, remove toxic or aged macromolecules and remodel the organelle upon physiologic or pathologic cues. H ...

2025

Phosphorus speciation in environmental organic matter using 31P-NMR. Recent advances in the characterization of atmospheric organic matter

Athanasios Nenes, Kalliopi Violaki, Christos Panagiotopoulos

Phosphorus (P) is a vital element for all living organisms and is one of the most essential nutrients in both aquatic and terrestrial ecosystems. As a fundamental component of DNA and RNA, it plays a structural role in cell membranes (e.g., as part of phos ...

2025

Enzymatic absorption promoters for non-invasive peptide delivery

Cristina Martin Olmos, Angela Steinauer

Peptide drugs offer considerable potential for treating a diverse range of diseases. Yet, their clinical application is generally restricted to injectable therapies. The main challenge hindering their broader use through globally accessible, patient-friend ...

2025

Modeling the mechanosensitive collective migration of cells on the surface and the interior of morphing soft tissues

Mahmut Selman Sakar, Jaemin Kim

Cellular contractility, migration, and extracellular matrix (ECM) mechanics are critical for a wide range of biological processes including embryonic development, wound healing, tissue morphogenesis, and regeneration. Even though the distinct response of c ...

Springer Science and Business Media LLC2024

Viral peptide conjugates for metal-warhead delivery to chromatin

Paul Joseph Dyson, Lucinda Kate Batchelor

The presence of heavy metal groups can endow compounds with unique structural and chemical attributes beneficial for developing highly potent therapeutic agents and effective molecular labels. However, metallocompound binding site specificity is a major ch ...

2024

From microbiome composition to functional engineering, one step at a time

Vassily Hatzimanikatis, Evangelia Vagena, Mohammadomid Oftadeh, Asli Sahin

Communities of microorganisms (microbiota) are present in all habitats on Earth and are relevant for agriculture, health, and climate. Deciphering the mechanisms that determine microbiota dynamics and functioning within the context of their respective envi ...

Amer Soc Microbiology2023

Flexible Sensor and Readout Circuitry for Continuous Ion Sensing in Sweat

Sandro Carrara, Ata Jedari Golparvar, Ali Meimandi

In this letter, we present a custom-designed and flexible readout circuitry for the characterization of flexible and planar electrolyte-gated carbon nanotube field-effect transistor-based biosensors for ammonium detection in sweat. We employed spray-deposi ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2023

Model biomolecular condensates have heterogeneous structure quantitatively dependent on the interaction profile of their constituent macromolecules

Julian Charles Shillcock

Biomolecular condensates play numerous roles in cells by selectively concentrating client proteins while excluding others. These functions are likely to be sensitive to the spatial organization of the scaffold proteins forming the condensate. We use coarse ...

2022

Three-Dimensional Confinement of Water: H2O Exhibits Long-Range (> 50 nm) Structure while D2O Does Not

Sylvie Roke, Nathan Dupertuis, Cornelis Ulrich Lütgebaucks, Orly Bagunu Tarun

Water is the liquid of life thanks to its three-dimensional adaptive hydrogen (H)-bond network. Confinement of this network may lead to dramatic structural changes influencing chemical and physical transformations. Although confinement effects occur on a < ...

AMER CHEMICAL SOC2022