Phage Selection of Bicyclic Peptide Ligands and Development of a New Peptide Cyclisation Method

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Proteins are the basic building blocks necessary for the operation and regulation of virtually all functions in living organisms. Over millions of years, evolution has created a vast repertoire of proteins finely tuned to execute their biological functions ...

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Many human cancers manifest the capability to circumvent attack by the adaptive immune system. In this work, we identified a component of immune evasion that involves frequent up-regulation of fragile X mental retardation protein (FMRP) in solid tumors. FM ...

Activin-A, a transforming growth factor ê µ family member, is a pleiotropic cytokine with diverse functions in development, fertility, adult tissue homeostasis, and aging. Accordingly, deregulation of Activin-A signaling has been associated with many patho ...

Light matter interactions such as extinction, reflection, and transmission can be described by classical optics. Dur-ing the past decades, research focused on a novel resonant extinction type called plasmonics that allows for en-hancement of both types of ...

Near-surface wind is difficult to estimate using global numerical weather and climate models, because airflow is strongly modified by underlying topography, especially that of a country such as Switzerland. In this article, we use a statistical approach ba ...

Glycan analysis has evolved considerably during the last decade. The advent of high-resolution ion-mobility spectrometry has enabled the separation of isomers with only the slightest of structural differences. However, the ability to separate such species ...

Phage Selection of Bicyclic Peptide Ligands and Development of a New Peptide Cyclisation Method

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Targeting molecular surfaces to engineer novel protein-based immunogens and inhibitors

Comparative Analysis of Total Alpha-Synuclein (alpha SYN) Immunoassays Reveals That They Do Not Capture the Diversity of Modified alpha SYN Proteoforms

Mechanical Immunoengineering of T Cells for Enhanced Cancer Immunotherapy

Aberrant hyperexpression of the RNA binding protein FMRP in tumors mediates immune evasion

Immunosuppressive roles of Activin-A in melanoma and characterization of its precursor cleavage

Engineering Absorption for Foil Applications

Downscaling of Historical Wind Fields over Switzerland Using Generative Adversarial Networks

Identification of Mobility-Resolved N-Glycan Isomers