Integrated Bio/Nano/CMOS Interfaces for Electrochemical Molecular Sensing

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Systems biology is a multidisciplinary field that weaves together all the basic sciences through the use of computational and bioinformatics tools, to provide a more integrative view of the complex molecular interactions taking place within and among cells ...

Background and Objectives: Red blood cells (RBCs) suffer from lesions during cold storage, depending in part on their ability to counterbalance oxidative stress by activating their antioxidant defence. The aim of this study was to monitor the antioxidant p ...

Metabolism is a network of biochemical reactions that converts carbon sources to cellu-lar fuels and building blocks. Metabolism of many organisms has been studied for many decades. These studies define metabolism as a very large and complex network. Stoic ...

Many tissues exhibit metabolic compartmentation. In the brain, while there is no doubt on the importance of functional compartmentation between neurons and glial cells, there is still debate on the specific regulation of pathways of energy metabolism at di ...

In wearable-based human activity recognition (HAR) research, one of the major challenges is the large intra-class variability problem. The collected activity signal is often, if not always, coupled with noises or bias caused by personal, environmental, or ...

Simultaneous prediction of wrist and hand motions is essential for the natural interaction with hand prostheses. In this paper, we propose a novel multi-out Gaussian process (MOGP) model and a multi-task deep learning (MTDL) algorithm to achieve simultaneo ...

This paper represents the extended version of the conference paper “Developing highly-integrated subcutaneous biochips for remote monitoring of human metabolism” pre- sented at the IEEE Sensors Conference 2012, and presents data on assembly, packaging and ...

Objective. Meralgia paresthetica (MP) is a mononeuropathy of the exclusively sensory lateral femoral cutaneous nerve (LFCN) that is difficult to treat with conservative treatments. Afferents from the LFCN enter the spinal cord through the dorsal root entry ...

A System-in-Package (SiP) concept for the 3D-integration of a Single Wall Carbon Nanotube (SWCNT) resonator with its CMOS driving electronics is presented. The key element of this advanced SiP is the monolithic 3D-integration of the MEMS with the CMOS elec ...

This paper contributes to the intersection of operations research and machine learning in the context of autonomous ridesharing. In this work, autonomous ridesharing operations are reproduced through an event-based simulation approach and are modeled as a ...

The interaction between water vapor and atmos-pheric aerosol leads to enhancement in aerosol water content,which facilitates haze development, but its concentrations, sources,and impacts remain largely unknown in polluted urban environ-ments. Here, we show ...

Polymer light-emitting electrochemical cells (PLECs) and light-emitting diodes (PLEDs) receive interest for large-area lighting and signage applications. During operation of a PLEC, a p-i-n junction develops where electrons and holes are injected into the ...

Resveratrol is a natural compound that affects energy metabolism and mitochondrial function and serves as a calorie restriction mimetic, at least in animal models of obesity. Here, we treated 11 healthy, obese men with placebo and 150 mg/day resveratrol (r ...

Microbial life is widespread in the terrestrial subsurface and present down to several kilometers depth, but the energy sources that fuel metabolism in deep oligotrophic and anoxic environments remain unclear. In the deep crystalline bedrock of the Fennosc ...

Huntington's disease (HD), an incurable neurodegenerative disorder, has a complex pathogenesis including protein aggregation and the dysregulation of neuronal transcription and metabolism. Here, we demonstrate that inhibition of sirtuin 2 (SIRT2) achieves ...

In this paper a novel approach to optimize digital integrated circuits yield with regards to speed and area/power for aggressive scaling technologies is presented. The technique is intended to reduce the effects of intra-die variations using redundancy app ...

Insects, like vertebrates, express iron regulatory proteins (IRPs) that may regulate proteins in cellular iron storage and energy metabolism. Two mRNAs, an unspliced form of ferritin H mRNA and succinate dehydrogenase subunit b (SDHb) mRNA, are known to co ...

Cellulose nanomaterials are developing nowadays as a promising environmental friendlier biomaterial that can be extracted from native plant sources. These materials, because of their excellent physico-chemical and biological properties, urged much interest ...

Integrated Bio/Nano/CMOS Interfaces for Electrochemical Molecular Sensing

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Computational methods and modeling of cellular function for the optimization of protein production and the study of cellular disease states

The antioxidant capacity of erythrocyte concentrates is increased during the first week of storage and correlated with the uric acid level

Navigating and Managing the Complexity of Genome Scale Metabolic Networks for Studies in Cellular Physiology and Industrial Biotechnology

Compartmentalised energy metabolism supporting glutamatergic neurotransmission in response to increased activity in the rat cerebral cortex: A 13C MRS study in vivo at 14.1 T

Learning Disentangled Behaviour Patterns for Wearable-based Human Activity Recognition

Simultaneous Prediction of Wrist and Hand Motions via Wearable Ultrasound Sensing for Natural Control of Hand Prostheses

A Subcutaneous Biochip for Remote Monitoring of Human Metabolism: Packaging and Biocompatibility Assessment

Targeted dorsal root entry zone stimulation alleviates pain due to meralgia paresthetica

High-temperature compatible 3D-integration processes for a vacuum-sealed CNT-based NEMS

A machine learning-driven two-phase metaheuristic for autonomous ridesharing operations

Ammonium Chloride Associated Aerosol Liquid Water Enhances Haze in Delhi, India br

Traps for Electrons and Holes Limit the Efficiency and Durability of Polymer Light-Emitting Electrochemical Cells

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Active anaerobic methane oxidation and sulfur disproportionation in the deep terrestrial subsurface

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis

Selective Redundancy-Based Design Techniques for the Minimization of Local Delay Variations

Differential translational regulation of IRE-containing mRNAs in Drosophila melanogaster by endogenous IRP and a constitutive human IRP1 mutant

Promising eco-friendly biomaterials for future biomedicine: Cleaner production and applications of Nanocellulose