Publications associées à Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype

Publications associées (14)

Predicting Attention Deficits and Functional Recovery After Glioma Resection Through Functional Executive Networks: Insights From Dynamic Properties

BackgroundPostoperative short-term attentional and executive dysfunctions are common after brain tumor resection, significantly impacting patients' quality of life and functional recovery. This longitudinal cross-sectional study investigated whether presur ...

SPRINGER2025

Uncertainty quantification for Fisher-Kolmogorov equation on graphs with application to patient-specific Alzheimer's disease

Alfio Quarteroni

The Fisher-Kolmogorov equation is a diffusion-reaction PDE that models the accumulation of prionic proteins, which are responsible for many different neurological disorders. The most important and studied misfolded protein in literature is the Amyloid-beta ...

EDP SCIENCES S A2024

CDKL5 sculpts functional callosal connectivity to promote cognitive flexibility

Valerio Zerbi

Functional and structural connectivity alterations in short- and long-range projections have been reported across neurodevelopmental disorders (NDD). Interhemispheric callosal projection neurons (CPN) represent one of the major long-range projections in th ...

SPRINGERNATURE2023

Combining hypothesis- and data-driven neuroscience modeling in FAIR workflows

Daniel Keller

Modeling in neuroscience occurs at the intersection of different points of view and approaches. Typically, hypothesis-driven modeling brings a question into focus so that a model is constructed to investigate a specific hypothesis about how the system work ...

2022

Estrogen-related receptor gamma regulates mitochondrial and synaptic genes and modulates vulnerability to synucleinopathy

Johan Auwerx

Many studies implicate mitochondrial dysfunction as a key contributor to cell loss in Parkinson disease (PD). Previous analyses of dopaminergic (DAergic) neurons from patients with Lewy-body pathology revealed a deficiency in nuclear-encoded genes for mito ...

NATURE PORTFOLIO2022

Learning-related congruent and incongruent changes of excitation and inhibition in distinct cortical areas

Carl Petersen, Sylvain Crochet, Romain Guiet, Georgios Foustoukos, Vahid Esmaeili, Yanqi Liu, Keita Tamura, Anastasiia Oryshchuk

Excitatory and inhibitory neurons in diverse cortical regions are likely to contribute differentially to the transformation of sensory information into goal-directed motor plans. Here, we investigate the relative changes across mouse sensorimotor cortex in ...

2022

Connectivity Measures Differentiate Cortical and Subcortical Sub-Acute Ischemic Stroke Patients

Silvestro Micera

Brain lesions caused by cerebral ischemia lead to network disturbances in both hemispheres, causing a subsequent reorganization of functional connectivity both locally and remotely with respect to the injury. Quantitative electroencephalography (qEEG) meth ...

FRONTIERS MEDIA SA2021

An assessment of intra-scanner reproducibility of myelin-sensitive MRI measures

Yi Wang, Meritxell Bach Cuadra, Cristina Granziera, Muhamed Barakovic, Francesco La Rosa, Lester Melie Garcia

SAGE PUBLICATIONS LTD2021

Converging intracortical signatures of two separated processing timescales in human early auditory cortex

Fabiano Baroni

Neural oscillations in auditory cortex are argued to support parsing and representing speech constituents at their corresponding temporal scales. Yet, how incoming sensory information interacts with ongoing spontaneous brain activity, what features of the ...

2020

Understanding ultrasound neuromodulation using a computationally efficient and interpretable model of intramembrane cavitation

Silvestro Micera, Esra Neufeld, Théo Lemaire

Objective. Low-intensity focused ultrasound stimulation (LIFUS) emerges as an attracting technology for noninvasive modulation of neural circuits, yet the underlying action mechanisms remain unclear. The neuronal intramembrane cavitation excitation (NICE) ...

2019

Layer, cell-type and pathway-specific thalamocortical input to mouse somatosensory cortex

Berat Semihcan Sermet

In the mouse whisker system, sensory information is relayed to the whisker somatosensory cortex by two major thalamic nuclei, the ventral posterior medial nucleus (VPM) and the posterior medial nucleus (POM). While the cortical axonal innervation pattern o ...

EPFL2018

Progress towards in vivo brain (13)C-MRS in mice: Metabolic flux analysis in small tissue volumes

Rolf Gruetter, Bernard Lanz, Marta Lai

The combination of dynamic (13)C MRS data under infusion of (13)C-labeled substrates and compartmental models of cerebral metabolism enabled in vivo measurement of metabolic fluxes with a quantitative and distinct determination of cellular-specific activit ...

Elsevier2017

Proteolytic processing of the synaptic cell adhesion molecule neurexin-3beta and the neurobiological functions of the resulting cleavage products

Magda Maria Palczynska

Neurexins are key synaptic cell adhesion molecules involved in synapse specification and maturation. They couple synaptic activity and cell adhesion to regulate activity-dependent synapse development. Recently, neurexin processing by alpha- and gamma- secr ...

EPFL2016

Dissociating effect of upper limb non-use and overuse on space and body representations

Andrea Serino, Michela Bassolino, Elisa Canzoneri

Accurate and updated representations of the space where the body acts, i.e. the peripersonal space (PPS), and the location and dimension of body parts (body representation, BR) are essential to perform actions. Because both PPS and BR are involved in motor ...

Pergamon-Elsevier Science Ltd2015