Publication

Essential role of endothelial Notch1 in angiogenesis

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Species-specific regulation of XIST by the JPX/FTX orthologs

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X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main trigger of XCI, is controlled in the mouse by an interplay of lncRNA genes (LRGs), some of which evolved concom ...

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In vitro endoderm emergence and self-organisation in the absence of extraembryonic tissues and embryonic architecture

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In humans, mice, and other mammals key internal organs such as the gut, the lungs, the pancreas, and the liver all derive from the same embryonic tissue: the endoderm. The development of all of these structures thus depends on a same set of early cells, an ...

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