Publication

Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep

Publications associées (32)

Multi T1-weighted contrast MRI with fluid and white matter suppression at 1.5 T

Introduction: The fluid and white matter suppression sequence (FLAWS) provides two T1-weighted co-registered datasets: a white matter (WM) suppressed contrast (FLAWS1) and a cerebrospinal fluid (CSF) suppressed contrast (FLAWS2). FLAWS has the potential to ...

ELSEVIER SCIENCE INC2019

Longitudinal study of neonatal brain tissue volumes in preterm infants and their ability to predict neurodevelopmental outcome

Djalel Eddine Meskaldji, Laura Ioana Gui, Serafeim Loukas

Premature birth has been associated with poor neurodevelopmental outcomes. However, the relation between such outcomes and brain growth in the neonatal period has not yet been fully elucidated. This study investigates longitudinal brain development between ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2019

Magnetization transfer in magnetic resonance fingerprinting

Tobias Kober, Tom Hilbert

Purpose To study the effects of magnetization transfer (MT, in which a semi-solid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF). Methods Simulations and phantom experiments were performed to study the im ...

WILEY2020

Towards quantitative brain connectomics: microstructure informed tractography via convex optimization

Muhamed Barakovic

Tractography is the only non-invasive technique which is used to reconstruct the white mat- ter structural connectivity of the human brain. It relies on a specific Magnetic Resonance Imaging (MRI) acquisition, called diffusion MRI, which is sensitive to th ...

EPFL2019

GABA and glutamate moderate beta-amyloid related functional connectivity in cognitively unimpaired old-aged adults

Dimitri Nestor Alice Van De Ville, Maria Giulia Preti

Background: Effects of beta-amyloid accumulation on neuronal function precede the clinical manifestation of Alzheimer's disease (AD) by years and affect distinct cognitive brain networks. As previous studies suggest a link between beta-amyloid and dysregul ...

2019

Quantitative brain relaxation atlases for personalized detection and characterization of brain pathology

Jean-Philippe Thiran, Reto Meuli, Guillaume Bonnier, Tobias Kober, Cristina Granziera, Tom Hilbert, Gian Franco Piredda

Purpose To exploit the improved comparability and hardware independency of quantitative MRI, databases of MR physical parameters in healthy tissue are required, to which tissue properties of patients can be compared. In this work, normative values for long ...

WILEY2020

Advantages of fluid and white matter suppression (FLAWS) with MP2RAGE compared with double inversion recovery turbo spin echo (DIR-TSE) at 7T

Tobias Kober

Cerebrospinal fluid (CSF) and white matter (WM) signal suppression techniques allow better visualization of both WM and gray matter (GM) lesions in such disorders as multiple sclerosis and epilepsy. Recently, a technique, FLuid And White matter Suppression ...

ELSEVIER IRELAND LTD2019

In vivo diffusion magnetic resonance imaging of the white matter microstructure from dictionaries generated by Monte Carlo simulations: development and validation

Gaëtan Olivier D Rensonnet

Non-invasive virtual histology of white matter tissues is the ultimate promise of diffusion-weighted MRI (DW-MRI). This hope is fueled by the exquisite sensitivity of DW-MRI to micrometer-scale displacement of diffusing water molecules, averaged over a who ...

EPFL2019

Brain tissue segmentation based on MP2RAGE multi-contrast images in 7 T MRI

Tobias Kober

We proposed a method for segmentation of brain tissues-gray matter, white matter, and cerebrospinal fluid-using multi-contrast images, including a T1 map and a uniform T1-weighted image, from a magnetization-prepared 2 rapid acquisition gradient echoes (MP ...

2019

Assessing feasibility and reproducibility of a bundle-specific framework on in vivo axon diameter estimates at 300mT/m

Jean-Philippe Thiran, Giorgio Innocenti, David Paul Roger Romascano, Alessandro Daducci, Muhamed Barakovic, Gabriel Girard, Maxime Descoteaux, Jonathan Rafael Patino Lopez

In vivo quantitative estimation of axon diameter in the white matter could bring new tools to study the structural and functional architecture of the brain. Recently, the feasibility of axon diameter estimation with diffusion-weighted MRI (DW-MRI) has been ...

2018

Exploring the role of white matter connectivity in cortex maturation

Patric Hagmann, Alessandra Griffa, Petra Susan Hüppi

The maturation of the cortical gray matter (GM) and white matter (WM) are described as sequential processes following multiple, but distinct rules. However, neither the mechanisms driving brain maturation processes, nor the relationship between GM and WM m ...

2017

Studying cyto and myeloarchitecture of the human cortex at ultra-high field with quantitative imaging: R1, R⁎2 and susceptibility

Rolf Gruetter, José Pedro Rebelo Ferreira Marques, Diana Khabipova

In this manuscript, the use of quantitative imaging at ultra-high field is evaluated as a mean to study cyto and myelo-architecture of the cortex. The quantitative contrasts used are the longitudinal relaxation rate (R1), apparent transverse relaxation rat ...

Elsevier2017