Publications associées à Brain microstructure alterations in subjective cognitive decline: a multi-component T2 relaxometry study

Publications associées (13)

Post stroke recovery prediction

Dimitri Nestor Alice Van De Ville, Elvira Pirondini

The present relates to a method for generating a graph representing a virtually lesioned connectome of a patient after a stroke comprising:- providing structural data of the brain of the patient after the stroke;- segmenting said structural data to delinea ...

2024

Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

Veronica Lily Ravano

Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

EPFL2024

Quantifying brain development in the HEALthy Brain and Child Development (HBCD) Study: The magnetic resonance imaging and spectroscopy protocol

Tobias Kober, Tom Hilbert

The HEALthy Brain and Child Development (HBCD) Study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The acqui ...

ELSEVIER SCI LTD2024

The hippocampus dissociates present from past and future goals

Maria Giulia Preti

Our brain adeptly navigates goals across time frames, distinguishing between urgent needs and those of the past or future. The hippocampus is a region known for supporting mental time travel and organizing information along its longitudinal axis, transitio ...

Nature Research2024

Axonal projections from mouse whisker-related sensory cortex

Yanqi Liu

Neurons primarily communicate through release of neurotransmitter from presynaptic specialisations along their axonal arborisations. In order to understand the functional role of a specific neuron, it is therefore of great interest to know the structure of ...

EPFL2023

CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Ludovic Pierre Gustave Keiser

The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether and how sensory cells in the central nervous system (CNS) become activated during bacteri ...

CELL PRESS2023

An attention-based deep learning approach for the classification of subjective cognitive decline and mild cognitive impairment using resting-state EEG

Silvestro Micera

Objective. This study aims to design and implement the first deep learning (DL) model to classify subjects in the prodromic states of Alzheimer's disease (AD) based on resting-state electroencephalographic (EEG) signals. Approach. EEG recordings of 17 heal ...

IOP Publishing Ltd2023

Neurogenesis redirects β-catenin from adherens junctions to the nucleus to promote axonal growth

Antonio Herrera Camacho

Here, we show that, in the developing spinal cord, after the early Wnt-mediated Tcf transcription activation that confers dorsal identity to neural stem cells, neurogenesis redirects beta-catenin from the adherens junctions to the nucleus to stimulate Tcfo ...

Company Biologists Ltd2023

Through-Plane Super-Resolution With Autoencoders in Diffusion Magnetic Resonance Imaging of the Developing Human Brain

Meritxell Bach Cuadra, Erick Jorge Canales Rodriguez, Gabriel Girard

Fetal brain diffusion magnetic resonance images (MRI) are often acquired with a lower through-plane than in-plane resolution. This anisotropy is often overcome by classical upsampling methods such as linear or cubic interpolation. In this work, we employ a ...

FRONTIERS MEDIA SA2022

PIRACY: An Optimized Pipeline for Functional Connectivity Analysis in the Rat Brain

Rolf Gruetter, Ileana Ozana Jelescu, Ting Yin, Yujian Diao

Resting state functional MRI (rs-fMRI) is a widespread and powerful tool for investigating functional connectivity (FC) and brain disorders. However, FC analysis can be seriously affected by random and structured noise from non-neural sources, such as phys ...

2021

Representations of time in human frontoparietal cortex

Wietske Van der Zwaag, Domenica Bueti

Precise time estimation is crucial in perception, action and social interaction. Previous neuroimaging studies in humans indicate that perceptual timing tasks involve multiple brain regions; however, whether the representation of time is localized or distr ...

2018

Mapping and characterization of positive and negative BOLD responses to visual stimulation in multiple brain regions at 7T

Rolf Gruetter, Wietske Van der Zwaag, Patricia Figueiredo, João Pedro Forjaco Jorge

External stimuli and tasks often elicit negative BOLD responses in various brain regions, and growing experimental evidence supports that these phenomena are functionally meaningful. In this work, the high sensitivity available at 7T was explored to map an ...

Wiley2018

Dendritic Excitability and Gain Control in Recurrent Cortical Microcircuits

Idan Segev

Layer 5 thick tufted pyramidal cells (TTCs) in the neocortex are particularly electrically complex, owing to their highly excitable dendrites. The interplay between dendritic nonlinearities and recurrent cortical microcircuit activity in shaping network re ...

2015