MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia

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Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR. Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...

Typically, a time-of-flight (TOF) positron emission tomography (PET) block detector is built using application-specific integrated circuits (ASICs), since they integrate a high number of channels at a reasonable power consumption and into a small area. How ...

Despite being a powerful medical imaging technique which does not emit any ionizing radiation, magnetic resonance imaging (MRI) always had the major problem of long scanning times that can take up to an hour depending on the application. It also requires u ...

A closed time-reversal (TR) cavity has been considered a purely theoretical concept whose experimental realization was assumed to be impossible. In this article, we demonstrate that it is, in fact, possible to realize a closed TR cavity using a network of ...

Balanced steady-state free precession (bSSFP) can be used as an alternative to gradient-echo (GE) EPI for BOLD functional MRI when image distortions and signal drop-outs are severe such as at ultra-high field. However, 3D-bSSFP acquisitions have distinct d ...

Recovering the distribution from multi-echo magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this work, we propose to comb ...

Since the seventies, positron emission tomography (PET) has become an invaluable medical molecular imaging modality with an unprecedented sensitivity at the picomolar level, especially for cancer diagnosis and the monitoring of its response to therapy. Mor ...

Early diagnosis of acute cartilage injuries enables monitoring of disease progression and improved treatment option planning to prevent post-traumatic osteoarthritis. In contrast-enhanced computed tomography (CECT), the changes in cationic agent diffusion ...

Dual contrast micro computed tomography (CT) shows potential for detecting articular cartilage degeneration. However, the performance of conventional CT systems is limited by beam hardening, low image resolution (full-body CT), and long acquisition times ( ...

Hyperpolarization in diamond via dynamic nuclear polarization (DNP) has attracted a lot of interest for various applications as diamond exhibits extremely long C-13 spin relaxation times and has endogenous polarizing agents in the form of crystalline defec ...

Background: Effects of beta-amyloid accumulation on neuronal function precede the clinical manifestation of Alzheimer's disease (AD) by years and affect distinct cognitive brain networks. As previous studies suggest a link between beta-amyloid and dysregul ...

Glucose utilization increases in tumors, a metabolic process that is observed clinically by F-18-fluorodeoxyglucose positron emission tomography (F-18-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are impl ...

MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia

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Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Methods to Enhance Nuclear Magnetic Resonance Sensitivity at High Magnetic Field

Toward a Full-Flexible and Fast-Prototyping TOF-PET Block Detector Based on TDC-on-FPGA

Data-driven Measurement Designs for Magnetic Resonance Imaging

A Closed Time-Reversal Cavity for Electromagnetic Waves in Transmission Line Networks

Multi-slice passband bSSFP for human and rodent fMRI at ultra-high field

Model-informed machine learning for multi-component T2 relaxometry

Roadmap toward the 10 ps time-of-flight PET challenge

Simultaneous Quantitation of Cationic and Non-ionic Contrast Agents in Articular Cartilage Using Synchrotron MicroCT Imaging

Synchrotron MicroCT Reveals the Potential of the Dual Contrast Technique for Quantitative Assessment of Human Articular Cartilage Composition

High-Field C-13 Dynamic Nuclear Polarization in Nanodiamond

GABA and glutamate moderate beta-amyloid related functional connectivity in cognitively unimpaired old-aged adults

Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth