Publications associées à Geometrical deployment for braided stent

Modified pressure-cooker technique (PCT) using extra-soft Kaneka coils improves embolization of high-grade cerebral arteriovenous malformations: a technical note

Endovascular embolization techniques are showing an extraordinary potential to treat patients suffering from complex neurovascular malformations. The embolization with liquid embolic agents via Onyx is a prominent approach to treat arteriovenous malformati ...

SPRINGERNATURE2023

Sensor-integrated ultraflexible endovascular devices

Lucio Feo Pancaldi-Giubbini

Medical interventions in the central nervous system (CNS) are challenging due to the complexity and delicacy of the brain tissue. Techniques that do not require opening the skull would alleviate patient discomfort and increase post-operative outputs. Vesse ...

EPFL2022

In situ photopolymerizable hydrogels for intracranial aneurysms treatment

Oriane Poupart

Intracranial aneurysm is a cerebrovascular disease characterized by an artery dilation in the brain. An aneurysm is prone to rupture, which causes a life-threatening subarachnoid hemorrhage. The major drawbacks of the current treatments, open surgical clip ...

EPFL2021

Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms

Dominique Pioletti, Andreas Schmocker, Lucio Feo Pancaldi-Giubbini, Christophe Moser, Mahmut Selman Sakar, Oriane Poupart

An alternative intracranial aneurysm embolic agent is emerging in the form of hydrogels due to their ability to be injected in liquid phase and solidify in situ. Hydrogels have the ability to fill an aneurysm sac more completely compared to solid implants ...

2021

Transient Neurovascular Interface for Minimally Invasive Neural Recording and Stimulation

Philippe Reymond, Diego Ghezzi, Laura Ferlauto, Adele Fanelli, Elodie Geneviève Zollinger

Neural interfaces are used to mitigate the burden of traumatic injuries, neurodegenerative diseases, and mental disorders. However, the transient or permanent placement of an interface in close contact with the neural tissue requires invasive surgery, pote ...

Wiley2021

In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms

Dominique Pioletti, Andreas Schmocker, Christophe Moser, Oriane Poupart

Intracranial aneurysms are increasingly being treated with endovascular therapy, namely coil embolization. Despite being minimally invasive, partial occlusion and recurrence are more frequent compared to open surgical clipping. Therefore, an alternative tr ...

2020

Neurovascular stent artifacts in 3D-TOF and 3D-PCMRI: Influence of stent design on flow measurement

Mohamed Farhat, Pierre Bouillot, Hasan Yilmaz

Purpose: The morphological and hemodynamic evaluations of neurovascular diseases treated with stents would benefit from noninvasive imaging techniques such as 3D time-of-flight MRI (3D-TOF) and 3D phase contrast MRI (3D-PCMRI). For this purpose, a comprehe ...

WILEY2019

How Flow Reduction Influences the Intracranial Aneurysm Occlusion: A Prospective 4D Phase-Contrast MRI Study

Mohamed Farhat, Philippe Reymond, Pierre Bouillot

BACKGROUND AND PURPOSE: Flow-diverter stents are widely used for the treatment of wide-neck intracranial aneurysms. Various parameters may influence intracranial aneurysm thrombosis, including the flow reduction induced by flow-diverter stent implantation, ...

American Society of Neuroradiology (ASNR)2019

Angiotensin II infusion into ApoE(-/-) mice: a model for aortic dissection rather than abdominal aortic aneurysm?

Nikolaos Stergiopoulos, Patrick Segers, Jessica Sordet, Alessandra Piersigilli, Bram Trachet, Lydia Aslanidou

Aims Angiotensin II-infused ApoE(-/-) mice are a popular mouse model for preclinical aneurysm research. Here, we provide insight in the often-reported but seldom-explained variability in shape of dissecting aneurysms in these mice. Methods and results N=45 ...

2017

Virtual-versus-Real Implantation of Flow Diverters: Clinical Potential and Influence of Vascular Geometry

Mohamed Farhat, Pierre Bouillot, Hasan Yilmaz

BACKGROUND AND PURPOSE: Intracranial stents have become extremely important in the endovascular management of complex intracranial aneurysms. Sizing and landing zone predictions are still very challenging steps in the procedure. Virtual stent deployment ma ...

American Society of Neuroradiology (ASNR)2016

Fast simulations of patient-specific haemodynamics of coronary artery bypass grafts based on a POD-Galerkin method and a vascular shape parametrization

Alfio Quarteroni, Gianluigi Rozza, Andrea Manzoni, Elena Faggiano

In this work a reduced-order computational framework for the study of haemodynamics in three-dimensional patient-specific configurations of coronary artery bypass grafts dealing with a wide range of scenarios is proposed. We combine several efficient algor ...

Elsevier2016

A numerical study of isotropic and anisotropic constitutive models with relevance to healthy and unhealthy cerebral arterial tissues

Alfio Quarteroni, Luca Dede', Paolo Tricerri, Adélia Sequeira

This paper presents an analysis of hyperelastic constitutive models for continuous bodies both from a modeling and numerical point of view. Contributions are made within the context of finite element numerical simulations. Numerical results with relevance ...

Elsevier2016

Intracranial Aneurysms: Wall Motion Analysis for Prediction of Rupture

Jean-Philippe Thiran

Intracranial aneurysms are a common pathologic condition with a potential severe complication: rupture. Effective treatment options exist, neurosurgical clipping and endovascular techniques, but guidelines for treatment are unclear and focus mainly on pati ...

Amer Soc Neuroradiology2015

Hemodynamic transition driven by stent porosity in sidewall aneurysms

Mohamed Farhat, Pierre Bouillot

The healing process of intracranial aneurysms (IAs) treated with flow diverter stents (FDSs) depends on the IA flow modifications and on the epithelization process over the neck. In sidewall IA models with straight parent artery, two main hemodynamic regim ...

Elsevier2015

Intra-aneurysmal hemodynamics: evaluation of pCONus and pCANvas bifurcation aneurysm devices using DSA optical flow imaging

Pierre Bouillot

Background Implantation of self-expanding stents from the parent artery into the sac of a bifurcation aneurysm is regularly used to facilitate endovascular coil occlusion with the so-called waffle cone technique (WCT). Self-expanding aneurysm bridging sten ...

BMJ2015

Dissecting abdominal aortic aneurysm in Ang II-infused mice: suprarenal branch ruptures and apparent luminal dilatation

Nikolaos Stergiopoulos, Patrick Segers, Jessica Sordet, Alessandra Piersigilli, Bram Trachet, Peter Modregger

Aims In this work, we provide novel insight into the morphology of dissecting abdominal aortic aneurysms in angiotensin II-infused mice. We demonstrate why they exhibit a large variation in shape and, unlike their human counterparts, are located suprarenal ...

Oxford University Press2015

Incidence, severity, mortality, and confounding factors for dissecting AAA detection in angiotensin II-infused mice: a meta-analysis

Nikolaos Stergiopoulos, Patrick Segers, Bram Trachet

Aims While angiotensin II-infused mice are the most popular model for preclinical aneurysm research, representative data on incidence, severity, and mortality of dissecting abdominal aortic aneurysms (AAAs) have never been established, and the influence of ...

Oxford University Press2015

Dissecting Abdominal Aortic Aneurysm in Angiotensin II-Infused Mice: The Importance of Imaging

Nikolaos Stergiopoulos, Patrick Segers, Alessandra Piersigilli, Bram Trachet

Introduction. Since the initial publication in 2000, Angiotensin II-infused mice have become one of the most popular models to study abdominal aortic aneurysm in a pre-clinical setting. We recently used phase contrast X-ray based computed tomography to dem ...

2015

Urban Planning in Africa: Which Alternative for Poor Cities? The Case of Koudougou in Burkina Faso

Jean-Claude Bolay

The efforts made to plan cities in emerging and developing countries are confronted to multiple issues, especially in small and middle sized cities which can be considered as poor through several criteria: socio-economic level of majority of population; lo ...

2015

Particle Imaging Velocimetry Evaluation of Intracranial Stents in Sidewall Aneurysm: Hemodynamic Transition Related to the Stent Design

Mohamed Farhat, Pierre Bouillot

We investigated the flow modifications induced by a large panel of commercial-off-the-shelf (COTS) intracranial stents in an idealized sidewall intracranial aneurysm (IA). Flow velocities in IA silicone model were assessed with and without stent implantati ...

Public Library of Science2014