Publication

Traction Forces Control Cell-Edge Dynamics and Mediate Distance Sensitivity during Cell Polarization

Publications associées (30)

Buckling instabilities and spatio-temporal dynamics of active elastic filaments

Biological filaments driven by molecular motors tend to experience tangential propulsive forces also known as active follower forces. When such a filament encounters an obstacle, it deforms, which reorients its follower forces and alters its entire motion. ...

ROYAL SOC2020

Integrin-Mediated Adhesion in the Unicellular Holozoan Capsaspora owczarzaki

Omaya Pierre Dudin

In animals, cell-matrix adhesions are essential for cell migration, tissue organization, and differentiation, which have central roles in embryonic development [1-6]. Integrins are the major cell surface adhesion receptors mediating cell-matrix adhesion in ...

CELL PRESS2020

Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis

Béatrice Kunz, Françoise Gisou van der Goot Grunberg, Laurence Gouzi Abrami, Matteo Dal Peraro, Shixu Yan, Luciano Andres Abriata

Capillary morphogenesis gene 2 (CMG2/ANTXR2) is a cell surface receptor for both collagen VI and anthrax toxin. Biallelic loss-of-function mutations in CMG2 lead to a severe condition, hyaline fibromatosis syndrome (HFS). We have here dissected a network o ...

Cell Press - Elsevier2020

Receptor-induced transient responses in cells with oscillatory actin dynamics

Jose Negrete Jr

Living cells adjust their sensing and migratory machinery in response to changes in their environment. In this work, we show that cells of the social amoeba Dictyostelium discoideum modulate the dynamical state of their actin cytoskeleton in response to an ...

AMER PHYSICAL SOC2020

Dynamics of optical forces and torques in plasmonic systems: a surface integral equation

Olivier Martin, Karim Achouri, Andrei Kiselev

A novel approach is introduced to determine the time evolution of optical forces and torques on arbitrary shape nanostructures by combining Maxwell's stress tensor with the surface integral equation method (SIE). Conventional time averaging of Maxwell’s st ...

SPIEDigitalLibrary2020

Adhesion of a tape loop

Harmeet Singh

In this work, we revisit experimentally and theoretically the mechanics of a tape loop. Using primarily elastic materials (polydimethylsiloxane, PDMS, or polycarbonate, PC) and confocal microscopy, we monitor the shape as well as the applied forces during ...

ROYAL SOC CHEMISTRY2020

Biophysically detailed mathematical models of multiscale cardiac active mechanics

Alfio Quarteroni, Francesco Regazzoni

Author summary Computer-based numerical simulations of the heart are increasingly assuming a recognized role in the context of computational medicine and cardiology. They are based on mathematical models describing the different physical phenomena occurrin ...

2020

Variational phase-field continuum model uncovers adhesive wear mechanisms in asperity junctions

Jean-François Molinari, Sylvain Collet

Wear is well known for causing material loss in a sliding interface. Available macroscopic approaches are bound to empirical fitting parameters, which range several orders of magnitude. Major advances in tribology have recently been achieved via Molecular ...

2020

Petrophysical properties of heavy oil-bearing carbonate rocks and their implications on petroleum system evolution: Insights from the Majella Massif

Carolina Giorgetti

In this work, we investigate the role of hydrocarbons in changing the petrophysical properties of rocks by merging laboratory measurements, outcrops characterization, and subsurface data focusing on a carbonate-bearing reservoir (Bolognano Formation) of th ...

2020

Multiaxial fatigue analysis of high-strength steel welded joints using generalized local approaches

Martin Antonio René Garcia

The objective of this thesis is to improve methods for predicting the fatigue life, multiaxial or not, of mild- and more particularly high-strength steels using local approaches that have the capacity to be applicable to almost any cases, hence the term ge ...

EPFL2020