Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia

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This study aims to determine whether 1) individuals with treatment-resistant schizophrenia display early cognitive impairment compared to treatment-responders and healthy controls and 2) N-methyl-D-aspartate-receptor hypofunction is an underlying mechanism ...

Reinforcement learning (RL) is crucial for learning to adapt to new environments. In RL, the prediction error is an important component that compares the expected and actual rewards. Dopamine plays a critical role in encoding these prediction errors. In my ...

A frequency scaling governor is critical for the performance management of cloud servers, as it enhances energy efficiency and helps to control operational temperatures, thereby ensuring system reliability. However, our in-depth analysis of the application ...

Fluorescence lifetime imaging (FLI) has been receiving increased attention in recent years as a powerful diagnostic technique in biological and medical research. However, existing FLI systems often suffer from a tradeoff between processing speed, accuracy, ...

We are constantly bombarded by sensory information and constantly making decisions on how to act. In order to optimally adapt behavior, we must judge which sequences of sensory inputs and actions lead to successful outcomes in specific circumstances. Neuro ...

Multiple lines of evidence across human functional, lesion, and animal data point to a cerebellar role, in particular of crus I, crus II, and lobule VIIB, in cognitive function. However, a mapping of distinct facets of cognitive function to cerebellar stru ...

How the 'what', 'where', and 'when' of past experiences are stored in episodic memories and retrieved for suitable decisions remains unclear. In an effort to address these questions, the authors present computational models of neural networks that behave l ...

The Python library ms3 makes scores (symbolic representations of music) operational for computational approaches by representing their contents as sets of tabular files. Music scores represent relations between sounding events by graphical means. The Free ...

Previous studies suggest that structural alteration of the corpus callosum, i.e., the largest white matter commissural pathway, occurs after a preterm birth in the neonatal period and lasts across development. The present study aims to unravel corpus callo ...

Dopamine synapses play a crucial role in volitional movement and reward-related behaviors, while dysfunction of dopamine synapses causes various psychiatric and neurological disorders. Despite this significance, the true biological nature of dopamine synap ...

The recollection of sensory information and subjective experience related to a personal past event depends on our episodic memory (EM). At the neural level, EM retrieval is linked with the reinstatement of hippocampal activity thought to recollect the sens ...

Over the course of a lifetime, the human brain acquires an astonishing amount of semantic knowledge and autobiographical memories, often with an imprinting strong enough to allow detailed information to be recalled many years after the initial learning exp ...

ObjectivePrematurity is associated with a high risk of long-term behavioral problems. This study aimed to assess the prognostic utility of volumetric brain data at term-equivalent-age (TEA), clinical perinatal factors, and parental social economic risk in ...

Understanding user’s perception of service variability is essential to discern their overall perception of any type of (transport) service. We study the perception of waiting time variability for ride-hailing services. We carried out a stated preference su ...

Information derived from experiences is incorporated into the brain as changes to ensembles of cells, termed engram cells, which allow memory storage and recall. The mechanism by which those changes hold specific information is unclear. Here, we test the h ...

The nucleus accumbens (NAc) is a brain hub regulating motivated behaviors, including social competitiveness. Mitochondrial function in the NAc links anxiety with social competitiveness, and the mitochondrial fusion protein mitofusin 2 (Mfn2) in NAc neurons ...

The transition towards a human-centered indoor climate is beneficial from occupants’ thermal comfort and from an energy reduction perspective. However, achieving this goal requires the knowledge of the thermal state of individuals at the level of body part ...

Aversively-motivated associative learning allows animals to avoid harm and thus ensures survival. Aversive learning can be studied by the fear learning paradigm, in which an innocuous sensory stimulus like a tone (conditioned stimulus, CS), acquires a nega ...

Empirical evidence shows that memories that are frequently revisited are easy to recall, and that familiar items involve larger hippocampal representations than less familiar ones. In line with these observations, here we develop a modelling approach to pr ...

During fear learning, defensive behaviors like freezing need to be finely balanced in the presence or absence of threat-predicting cues (conditioned stimulus, CS). Nevertheless, the circuits underlying such balancing are largely unknown. Here, we investiga ...

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia

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Neurocognition and NMDAR co-agonists pathways in individuals with treatment resistant first-episode psychosis: a 3-year follow-up longitudinal study

Unveiling the complexity of learning and decision-making

Is the powersave governor really saving power?

Coupling a recurrent neural network to SPAD TCSPC systems for real-time fluorescence lifetime imaging

Striatal Dopamine Signals and Reward Learning

The Cerebellum and Cognitive Function: Anatomical Evidence from a Transdiagnostic Sample

Computational models of episodic-like memory in food-caching birds

ms3: A parser for MuseScore files, serving as data factory for annotated music corpora

Corpus callosum structural characteristics in very preterm children and adolescents: Developmental trajectory and relationship to cognitive functioning

GABAergic-like dopamine synapses in the brain

Bodily self-consciousness as a framework to link sensory information and self-related components of episodic memory: behavioral, neuroimaging, and clinical evidence

A theory of memory consolidation and synaptic pruning in cortical circuits

Behavioral outcome of very preterm children at 5 years of age: Prognostic utility of brain tissue volumes at term-equivalent-age, perinatal, and environmental factors

An instance-based learning approach for evaluating the perception of ride-hailing waiting time variability

Engram cell connectivity as a mechanism for information encoding and memory function

Mitofusin-2 in nucleus accumbens D2-MSNs regulates social dominance and neuronal function

Toward contactless human thermal monitoring: A framework for Machine Learning-based human thermo-physiology modeling augmented with computer vision

Plasticity of sensory representations in the posterior insular cortex during fear learning

A dynamic attractor network model of memory formation, reinforcement and forgetting

A striatal circuit balances learned fear in the presence and absence of sensory cues