Publication

A Theoretical Study on the Reactivity of a Rhenium Hydroxo-Carbonyl Complex Towards beta-Lactams

Publications associées (29)

Novel Applications of Nitrous Oxide and Transition Metals for C-C and C-N Bond Formation

This thesis describes novel methods for and investigations into C–C and C–N bond formation reactions. Chapter 1 gives a very brief overview of established strategies for the formation of new C–C bonds in organic synthesis. In chapter 2, a multi‐step one‐po ...

EPFL2015

Cryogenic Spectroscopy and Quantum Molecular Dynamics Determine the Structure of Cyclic Intermediates Involved in Peptide Sequence Scrambling

Thomas Rizzo, Ursula Röthlisberger, Oleg Aseev, Marta Andreia Da Silva Perez

Collision-induced dissociation (CID) is a key technique used in mass spectrometry-based peptide sequencing. Collisionally activated peptides undergo statistical dissociation, forming a series of backbone fragment ions that reflect their amino acid (AA) seq ...

2015

Time-resolved X-ray and Optical Studies of Metalloproteins and Iridium Complexes

Mahsa Silatani

A wide variety of physicochemical processes at a molecular level, in particular charge or energy transfer, electronic and vibrational relaxation, are at the origin of biological functionality of proteins and organometallic compounds. The work reported in t ...

EPFL2015

Mimicking Enzymatic Active Sites on Surfaces for Energy Conversion Chemistry

Klaus Kern, Sebastian Stepanow, Magalí Alejandra Lingenfelder

Metal organic supramolecular chemistry on surfaces has matured to a point where its underlying growth mechanisms are well understood and structures of defined coordination environments of metal atoms can be synthesized in a controlled and reproducible proc ...

Amer Chemical Soc2015

Large-Scale Conformational Transitions and Dimerization Are Encoded in the Amino-Acid Sequences of Hsp70 Chaperones

Paolo De Los Rios, Duccio Malinverni, Alessandro Barducci

Hsp70s are a class of ubiquitous and highly conserved molecular chaperones playing a central role in the regulation of proteostasis in the cell. Hsp70s assist a myriad of cellular processes by binding unfolded or misfolded substrates during a complex bioch ...

Public Library Science2015

Efficient and Rapid Synthesis of Chlorido-Bridged Half-Sandwich Complexes of Ruthenium, Rhodium, and Iridium by Microwave Heating

Kay Severin, Rosario Scopelliti, Zacharias Immanuel Grote, Julie Risse, Justus Tönnemann

The dinuclear complexes [(p-cymene)RuCl2]2 and [(cyclopentadienyl)MCl2]2 (M = Ru, Rh, Ir) are important starting materials in organometallic chemistry. The standard synthesis of these complexes involves heating of an alcoholic solution of RuIII, RhIII, or ...

Wiley-Blackwell2013

Benign synthesis of the unsymmetrical ligand N-(quinolin-8-yl) pyrazine-2-carboxamide. Preparation, electrochemistry, antibacterial activity, and crystal structures of Cu(II) and Zn(II) complexes

Farzaneh Fadaei Tirani

Hqpzc has been synthesized by a highly efficient procedure using the ionic liquid TBAB as an environmentally benign reaction medium. [Cu(qpzc)(OAc)]H2O (1) and [Zn(qpzc)(OAc)(H2O)] (2), complexes of the deprotonated ligand, qpzc [qpzc ...

Taylor & Francis Ltd2013

Metal-based Chemosensors for Carbohydrates and Biologically Important Ligands

Vera Janowski

Chemosensors based on indicator displacement were developed for the optical detection of different analytes in aqueous solution. The sensing of carbohydrates, including glucose, in aqueous solution at pH 7.4 was achieved by a fluorescent indicator displace ...

EPFL2012

Multiple Isomers and Protonation Sites of the Phenylalanine/Serine Dimer

Thomas Rizzo, Ulrich Lorenz

Our investigation of the phenylalanine/serine (Phe/Ser) protonated dimer suggests that the intermolecular interaction between the two amino acids is more complex than could have been anticipated from previous studies of similar systems. Isomer-specific inf ...

2012