Publication

Shear stress alterations in the celiac trunk of patients with a continuous-flow left ventricular assist device as shown by in-silico and in-vitro flow analyses

Publications associées (30)

Integrated Electronics for Deep Implants to Remotely Monitor Hemodynamics

The integration of technology in the medical field has greatly improved accuracy in diagnoses, thus leading to more effective treatments. Wearable and implantable medical devices offer great potential for remote patient monitoring, particularly for heart f ...

EPFL2023

Reduced order modeling of parametrized pulsatile blood flows: Hematocrit percentage and heart rate

Ricardo Reyes Sotomayor

This paper numerically evaluates the accuracy and performance of a stabilized finite element Reduced Order Modelling (ROM) approach that is designed to simulate pulsatile blood flows. The method is able to estimate fluid flow parametric solutions of intere ...

PERGAMON-ELSEVIER SCIENCE LTD2023

A comprehensive mathematical model for cardiac perfusion

Alfio Quarteroni, Christian Vergara, Francesco Regazzoni

The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...

Nature Portfolio2023

Efficient approximation of cardiac mechanics through reduced-order modeling with deep learning-based operator approximation

Alfio Quarteroni, Andrea Manzoni

Reducing the computational time required by high-fidelity, full-order models (FOMs) for the solution of problems in cardiac mechanics is crucial to allow the translation of patient-specific simulations into clinical practice. Indeed, while FOMs, such as th ...

Wiley2023

Causal inference with recurrent and competing events

Matias Janvin, Mats Julius Stensrud, Pal Christie Ryalen

Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effects on hospitalizations in heart failure patients and sports injuries in ath ...

SPRINGER2023

Effect of the structural modification of Candesartan with Zinc on hypertension and left ventricular hypertrophy

Nikolaos Stergiopoulos, Augusto Martins Lima, Valeria Romina Martinez

Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart failure progression. Candesartan (Cand) is an angiotensin receptor antagonist widely used for hypertension treatment. Structural modifications were previously perf ...

ELSEVIER2023

Multisensing wearables for real-time monitoring of sweat electrolyte biomarkers during exercise and analysis on their correlation with core body temperature

Danick Briand, Silvia Demuru, Brince Paul Kunnel, Jaemin Kim, Vincent Gremeaux, Shu Wang

Sweat secreted by the human eccrine sweat glands can provide valuable biomarker information during exercise. Real-time non-invasive biomarker recordings are therefore useful for evaluating the physiological conditions of an athlete such as their hydration ...

2023

Interrelation between cardiac and brain small-vessel disease: a pilot quantitative PET and MRI study

Bénédicte Marie Maréchal, Ricardo Alberto Corredor Jerez

Background: Small-vessel disease (SVD) plays a crucial role in cardiac and brain ischemia, but little is known about potential interrelation between both. We retrospectively evaluated 370 patients, aiming at assessing the interrelation between cardiac and ...

Springernature2023

Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy

Alessia De Masi

The natural compound Cyclo Histidine-Proline (CHP) was initially discovered in the brain, but thereafter evaluated in the context of diabetes because of its hypoglycemic action. The pharmacokinetics and the toxicological profile of CHP showed it can be dos ...

EPFL2023

Design and computational optimization of compliance-matching aortic grafts

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas

Introduction: Synthetic vascular grafts have been widely used in clinical practice for aortic replacement surgery. Despite their high rates of surgical success, they remain significantly less compliant than the native aorta, resulting in a phenomenon calle ...

FRONTIERS MEDIA SA2023