Publication

On-chip antibody handling and colorimetric detection in a magnetic droplet manipulation system

Publications associées (32)

Analytic modelling of passive microfluidic mixers

Christophe Lallement, Jean-Michel Sallese

This paper deals with a new analytical model for microfluidic passive mixers. Two common approaches already exist for such a purpose. On the one hand, the resolution of the advection-diffusion-reaction equation (ADRE) is the first one and the closest to ph ...

AMER INST MATHEMATICAL SCIENCES-AIMS2022

A microfluidic Braille valve platform for on-demand production, combinatorial screening and sorting of chemically distinct droplets

Wenwei Ma, Christoph Merten, Vida Vafaizadeh

Droplet microfluidics is a powerful tool for a variety of biological applications including single-cell genetics, antibody discovery and directed evolution. All these applications make use of genetic libraries, illustrating the difficulty of generating che ...

NATURE PORTFOLIO2022

Systematic analysis of biomolecular binding reactions using microfluidic systems

Amir Shahein

Transcription factor binding to a single binding site on DNA and its functional consequence in a promoter context are beginning to be relatively well understood. However, binding to clusters of sites has yet to be characterized in depth, and the functional ...

EPFL2022

Prediction of Dispersion Rate of Airborne Nanoparticles in a Gas-Liquid Dual-Microchannel Separated by a Porous Membrane: A Numerical Study

Carlotta Guiducci, Zohreh Sheidaei

Recently, there has been increasing attention toward inhaled nanoparticles (NPs) to develop inhalation therapies for diseases associated with the pulmonary system and investigate the toxic effects of hazardous environmental particles on human lung health. ...

MDPI2022

Study of the enhanced electricity output of a sliding droplet-based triboelectric nanogenerator for droplet sensor design

Jürgen Brugger, Xia Liu, Wei Xu, Xiaopeng Li

Triboelectric nanogenerators are establishing themselves as promising candidates for realizing high-efficient energy harvesting from largely available droplets. However, the conventional droplet-based liquid-solid triboelectric nanogenerator (DLS-TENG) has ...

Elsevier2022

A neural probe to sample brain fluid in nanoliter volumes for quantitative molecular studies

Joan Teixidor

Neural functions operate in tightly controlled conditions that are mediated by multiple electrical and chemical phenomena. Brain disorders such as Parkinson's Disease and Alzheimer's Disease perturb these conditions and cause a loss of neurons, which impai ...

EPFL2022

Microfluidic study in a meter-long reactive path reveals how the medium’s structural heterogeneity shapes MICP-induced biocementation

Lyesse Laloui, Dimitrios Terzis, Ariadni Elmaloglou

Microbially induced calcium carbonate (CaCO3) precipitation (MICP) is one of the major sustainable alternatives to the artificial cementation of granular media. MICP consists of injecting the soil with bacterial- and calcium-rich solutions sequentially to ...

Nature Research2022

Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation

Thomas Lehnert, Martinus Gijs, Lin Sun

DNA fragmentation is an essential process in developing genetic sequencing strategies, genetic research, as well as for the diagnosis of diseases with a genetic signature like cancer. Efficient on-chip DNA fragmentation protocols would be beneficial to pro ...

ROYAL SOC CHEMISTRY2022

Deformation and Fracture of Tough Microstructured Hydrogels

Michael David Kessler

Many natural materials are structured on different length scales. This structuring often leads to an intricate interplay between soft and stiff components, which significantly improves the fracture toughness of these materials. A class of soft material tha ...

EPFL2022

Microscale hydrodynamic confinements: shaping liquids across length scales as a toolbox in life sciences

Philippe Renaud, David Philipp Taylor, Prerit Mathur

Hydrodynamic phenomena can be leveraged to confine a range of biological and chemical species without needing physical walls. In this review, we list methods for the generation and manipulation of microfluidic hydrodynamic confinements in free-flowing liqu ...

ROYAL SOC CHEMISTRY2022

The Dynamics of Single-Cell Nanomotion Behaviour of Saccharomyces cerevisiae in a Microfluidic Chip for Rapid Antifungal Susceptibility Testing

Sandor Kasas, María Inés Villalba

The fast emergence of multi-resistant pathogenic yeasts is caused by the extensive-and sometimes unnecessary-use of broad-spectrum antimicrobial drugs. To rationalise the use of broad-spectrum antifungals, it is essential to have a rapid and sensitive syst ...

MDPI2022

An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates

Matthias Lütolf, Sebastian Maerkl, Zoe Newell Swank, Stefano Davide Vianello, Julia Tischler, Hao-An Hsiung

We present a low-cost, do-it-yourself system for complexmammalian cell culture under dynamically changing medium formulations by integrating conventional multi-well tissue culture plates with simple microfluidic control and system automation. We demonstrat ...

2022