Publication

Allosteric Optical Control of a Class B G-Protein-Coupled Receptor

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Introduction: Regulation of endogenous glucose production (EGP) is essential for glucose homeostasis. It includes gluconeogenesis (GNG) from non-carbohydrate substrates and hepatic glycogenolysis. Both these pathways are dysregulated in acute stress, but t ...

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Covalent and Noncovalent Conjugation of Degradable Polymer Nanoparticles to T Lymphocytes

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Growth differentiation factor 15 protects against the aging-mediated systemic inflammatory response in humans and mice

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Mitochondrial dysfunction is associated with aging-mediated inflammatory responses, leading to metabolic deterioration, development of insulin resistance, and type 2 diabetes. Growth differentiation factor 15 (GDF15) is an important mitokine generated in r ...

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