Effects of MRI scan acceleration on brain volume measurement consistency

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Neurodegenerative and neuroinflammatory disorders often involve complex pathophysiological mechanisms that are â to this date â only partially understood. A more comprehensive understanding of those microstructural processes and their characterization ...

AIM: To characterise the corticoreticular pathway (CRP) in a case -control cohort of adolescent idiopathic scoliosis (AIS) patients using high -resolution slice -accelerated readoutsegmented echo -planar diffusion tensor imaging (DTI) to enhance the discri ...

Purpose: This study aims to evaluate two distinct approaches for fiber radius estimation using diffusion-relaxation MRI data acquired in biomimetic microfiber phantoms that mimic hollow axons. The methods considered are the spherical mean power-law approac ...

Constrained Spherical Deconvolution (CSD) is a state-of-the-art technique for unraveling complex fiber configurations of white matter from diffusion MRI data. Despite its ability to identify multiple fiber orientations, it faces difficulties in resolving f ...

We enable the estimation of the per-axon axial diffusivity from single encoding, strongly diffusion-weighted, pulsed gradient spin echo data. Additionally, we improve the estimation of the per-axon radial diffusivity compared to estimates based on spherica ...

ObjectiveWall shear stress (WSS) and its derived spatiotemporal parameters have proven to play a major role on intracranial aneurysms (IAs) growth and rupture. This study aims to demonstrate how ultra-high field (UHF) 7 T phase contrast magnetic resonance ...

Type C hepatic encephalopathy (HE) is a severe neuropsychiatric complication of chronic liver disease, for which the prognosis is poor in the absence of liver transplantation. Cirrhosis in type C HE leads to a toxic accumulation of ammonia in the blood, wh ...

Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values acqu ...

Objectives Fluid and white matter suppression (FLAWS) is a recently proposed magnetic resonance sequence derived from magnetization-prepared 2 rapid acquisition gradient-echo providing 2 coregistered datasets with white matter- and cerebrospinal fluid-supp ...

Diamond magnetometry makes use of fluorescent defects in diamonds to convert magnetic resonance signals into fluorescence. Because optical photons can be detected much more sensitively, this technique currently holds several sensitivity world records for r ...

Magnetic Resonance Imaging (MRI) is an established technique to study in vivo neurological disorders such as Multiple Sclerosis (MS). To avoid errors on MRI data organization and automated processing, a standard called Brain Imaging Data Structure (BIDS) h ...

This work focuses on obtaining a magnetic resonance imaging (MRI) signal representation that accounts for a longitudinal T-1 and transverse T-2* relaxations while at the same time integrating directional diffusion in the context of scattered multi-parametr ...

Backgrounds: Multiple sclerosis (MS) is an inveterate phlogistic situation characterized by focal and vaguely diffusive de-myelination and neurodegeneration, in the sphere of central nervous system (CNS). The brain's chronic inflammatory reaction includes ...

Magnetic Resonance Imaging combined with hyperpolarized C-13-labelled metabolic contrast agents produced via dissolution Dynamic Nuclear Polarization can, non-invasively and in real-time, report on tissue specific aberrant metabolism. However, hyperpolariz ...

Today, Magnetic Resonance Imaging (MRI) is a well-established medical imaging modality thanks to its excellent soft tissue contrast. Conventional MR image contrasts can be weighted towards one or more physical properties that discriminate different tissues ...

Functional magnetic resonance Brain Imaging (fMRI) is a key non-invasive imaging technique for the study of human brain activity. Its millimetric spatial resolution is at the cost of several constraints: participants must remain static and experience artif ...

The functional organization of neural processes is constrained by the brain's intrinsic structural connectivity, i.e., the connectome. Here, we explore how structural connectivity can improve the representation of brain activity signals and their dynamics. ...

Magnetic nanoparticle based hyperthermia emerged as a potential tool for treating malignant tumours. The efficiency of the method relies heavily on the knowledge of magnetic properties of the samples; in particular, knowledge of the frequency dependent com ...

MR is a well-established technique routinely used in preclinical and clinical studies. This thesis focussed on the improvement of sensitivity of different methods in MR. Hyperpolarized 129Xe gas is used for studying pulmonary disease or cerebral perfusion ...

Dissolution dynamic nuclear polarization (dDNP) is a powerful technique that enhances the magnetic resonance signal of nuclear spins by several orders of magnitude. DNP relies on the principle of cross-relaxation by electron spins driven out of equilibrium ...

Effects of MRI scan acceleration on brain volume measurement consistency

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Development and clinical validation of computational imaging biomarkers for neurodegenerative diseases

The hindbrain and cortico-reticular pathway in adolescent idiopathic scoliosis

Pore size estimation in axon-mimicking microfibers with diffusion-relaxation MRI

Spatial Prior Informed Constrained Spherical Deconvolution in Super Resolution Variation

Axial and radial axonal diffusivities and radii from single encoding strongly diffusion-weighted MRI

Near-wall hemodynamic parameters quantification in in vitro intracranial aneurysms with 7 T PC-MRI

New insights into rodent brain microstructure and metabolism in hepatic encephalopathy

Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions

3-Dimensional Fluid and White Matter Suppression Magnetic Resonance Imaging Sequence Accelerated With Compressed Sensing Improves Multiple Sclerosis Cervical Spinal Cord Lesion Detection Compared With Standard 2-Dimensional Imaging

Diamond-Based Nanoscale Quantum Relaxometry for Sensing Free Radical Production in Cells

BMAT: An open-source BIDS managing and analysis tool

Diffusion-relaxation scattered MR signal representation in a multi-parametric sequence

Fractal analysis in the quantification of medical imaging associated with multiple sclerosis pathology

Metabolic contrast agents produced from transported solid C-13-glucose hyperpolarized via dynamic nuclear polarization

Quantitative Microstructural Imaging for Clinical Use

Virtual Reality platform for functional Magnetic Resonance Imaging in Ecologically valid conditions

The connectome spectrum as a canonical basis for a sparse representation of fast brain activity

Non-exponential magnetic relaxation in magnetic nanoparticles for hyperthermia

Methods to Enhance Nuclear Magnetic Resonance Sensitivity at High Magnetic Field

Mechanistic studies of DNP and applications of hyperpolarized probes to study renal physiology and metabolism